Results 21 to 30 of about 3,224,146 (301)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

A framework for optimisation and techno-economic analysis of CO2 pressurisation strategies for pipeline transportation

open access: yesScience and Technology for Energy Transition
This paper presents a framework for optimisation and techno-economic analysis of various pressurisation pathways for CO2 pipeline transportation. The pressurisation pathways include a conventional compression only case from initial to final pressure, a ...
Andreasen Anders   +2 more
doaj   +1 more source

Does zero tillage save or increase production costs? Evidence from smallholders in Kyrgyzstan

open access: yesInternational Journal of Agricultural Sustainability, 2023
Promoting zero tillage has been recognized as an important strategy for smallholders from an agronomic perspective. However, the economic effects of adopting zero tillage are still a matter of debate. Employing an endogenous switching regression model on
Abdusame Tadjiev   +2 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

A framework for conceptualizing and assessing the resilience of essential services produced by socio-technical systems

open access: yesEcology and Society, 2018
Essential services such as electricity are critical to human well-being and the functioning of modern society. These services are produced by complex adaptive socio-technical systems and emerge from the interplay of technical infrastructure with people ...
Susara E. van der Merwe   +2 more
doaj   +1 more source

Numerical Model of Cloud-to-Ground Lightning for PyroCb Thunderstorms

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023
This paper demonstrates a 2-D numerical model to represent two conceptual pyrocumulonimbus (pyroCb) thundercloud structures: i) tilted dipole and ii) tripole structure with enhanced lower positive charge layer, which are hypothesized to explain the ...
Surajit Das Barman   +3 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

How to visualize electricity consumption anomalies: The impact of chart types on triggered emotions and eye movements

open access: yese-Prime: Advances in Electrical Engineering, Electronics and Energy, 2023
Home Energy Management Systems (HEMS) show anomalies and unusual patterns of the electricity consumption of households, usually in the form of charts.
Thomas P. Kremsner   +3 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

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