Results 61 to 70 of about 8,161,910 (315)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Prospects for offshore hydrogen production in the Netherlands

Environmental Research: Energy
Using a technology-rich optimization model for the Netherlands, we analyse the potential role of offshore energy options for system integration purposes.
Joost van Stralen, Gaby Janssen, Joris Koornneef, Martin Scheepers, Jeffrey Sipma, Bob van der Zwaan   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

State Transition Algorithm

, 2012
In terms of the concepts of state and state transition, a new heuristic random search algorithm named state transition algorithm is proposed. For continuous function optimization problems, four special transformation operators called rotation ...
A. H. Wright, A. K. Qin, C. Hamzacebi, C. Hamzacebi, D. D. Burgess, D. E. Goldberg, D. H. Wolpert, D. W. Stroock, F. J. Solis, F. V. Berth, G. Albeanu, G. Rudolph, H. A. Abbass, J. A. Nelder, J. C. Lagarias, J. J. Liang, J. Kennedy, J. Matyas, J. Y. Li, K. Deb, K. F. C. Yiu, P. Collet, R. C. Eberhart, R. Hooke, R. Storn, T. D. Tran, T. W. Leung, T. Zhang, X. J. Zhou, X. J. Zhou, X. S. Yang, Y. H. Shi, Y. X. Yuan, Z. Michalewicz   +33 more
core   +1 more source

Transitions in Urban Waterfronts: Imagining, Contesting, and Sustaining the Aquatic/Terrestrial Interface [PDF]

, 2021
Anne Taufen, Ken Yocom
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Wildfire Impacts on Security of Electric Power Systems: A Survey of Risk Identification and Mitigation Approaches

IEEE Access
The increase of extremely hot days globally has led to more frequent wildfires and frequent power outages directly and indirectly caused by the wildfires.
Rakibuzzaman Shah, Nima Amjady, Nusrat Subah Binte Shakhawat, Muhammad Usman Aslam, MD. Sazal Miah   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source