Results 201 to 210 of about 2,405,636 (294)

Moving-Target Tracking in Airport Airside Operations Using AIMM-STUKF. [PDF]

Sensors (Basel)
Gao J, Dang Y, Zhu Y, Xue W.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Preventing Disruptions in HIV Service Delivery to Key Populations During Project Transition From an International to a Local Implementing Partner: A Case Study From Zambia. [PDF]

Glob Health Sci Pract
Oladele EA, Musheke M, Mulenga F, Samona A, Iyamu I, Phiri A, Phiri N, Chabikuli ON.   +7 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Enhancer Trajectories in Lineage Commitment: Regulatory Logic of States and Cooperation. [PDF]

Biomolecules
Oh M, Jeong S, Kang K, Kim SK.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Zn-flux-enabled synthesis of orthorhombic kagome YbFe₆Ge₆: Yb reduction and magnetic behavior.

Chem Commun (Camb)
Meduri R, Wilkinson GR, Idrees MZ, Wei K, Stoian SA, La Pierre HS, McCandless GT, Chan JY.   +7 more
europepmc   +1 more source

Manifestations of Boron-Alkali Metal and Boron-Alkaline-Earth Metal Romances. [PDF]

Acc Chem Res
Cui ZH, Cui LJ, Barroso J, Guo JC, Zhai HJ, Pan S, Merino G.   +6 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source