Results 181 to 190 of about 451,806 (340)

JUND plays a genome-wide role in the quiescent to contractile switch in the pregnant human myometrium. [PDF]

PLoS Genet
Khader N, Dorogin A, Shynlova O, Mitchell JA.   +3 more
europepmc   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

A coordinated multidisciplinary model of care is needed for child and family centered care in pediatric genetic cancer risk services: a scoping review. [PDF]

Fam Cancer
Grant AM, Taylor N, Maguire J, de Graves S, Signorelli C, Fuentes-Bolanos NA, Tucker KM, Cruickshank M.   +7 more
europepmc   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Species-specific circular RNA circDS-1 enhances adaptive evolution in Talaromyces marneffei through regulation of dimorphic transition. [PDF]

PLoS Genet
Hu X, Du M, Tao C, Wang J, Zhang Y, Jin Y, Yang E.   +6 more
europepmc   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Transition in inherited metabolic diseases: the dietitians, pediatricians and adult physicians' point of view: the results of an Italian survey. [PDF]

Orphanet J Rare Dis
Rossi A, Pancaldi C, Regazzi MG, Agnelli G, Assirelli V, Barbato A, Baronio F, Benso A, Bernabei SM, Biasucci G, Botti M, Bonfanti C, Bordugo A, Bruni G, Burlina A, Candela E, Carbone MT, Carella R, Carubbi F, Cianflone A, Cipriani A, Coacci S, Da Prato G, De Leo S, Di Natale V, Dianin A, Dionisi Vici C, Fasan I, Ferraro S, Filosto M, Gasperini S, Giorda S, Gugelmo G, Guzzetti C, Latina C, Loro C, Maines E, Marchi G, Massimino E, Mita D, Nardecchia F, Noto D, Ortolano R, Paci S, Parini R, Parolisi S, Paterno G, Pontillo L, Pozzoli A, Pretese R, Quattrini S, Re Dionigi A, Rovelli V, Salera S, Santini F, Scala I, Sechi A, Sgattoni C, Stecchi M, Tavian A, Toscano A, Tummolo A, Urban ML, Verrecchia E, Vitturi N, Zuppaldi C, Zuvadelli J, Brodosi L.   +67 more
europepmc   +1 more source

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

Molecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

CDC6 Inhibits CDK1 Activity in MII-Arrested Oocyte Cell-Free Extract. [PDF]

Int J Mol Sci
Dillac L, Porębska K, Kloc M, Piprek RP, Tassan JP, Kubiak JZ.   +5 more
europepmc   +1 more source

When ecology meets genetics: Towards an integrated understanding of mating system transitions and diversity

, 2018
Sylvain Billiard, Henrique Teotónio
openalex   +2 more sources