Results 211 to 220 of about 172,050 (245)
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Genetics of transitional cell carcinoma
Seminars in Surgical Oncology, 1992AbstractSeveral models of genetic events which define the origin and progression of human tumors have been elucidated over the last several years. These models suggest that the study of tumors at the level of both the chromosome and the gene can be useful in elucidating molecular events in tumor progression and in determining the biologic behavior of ...
E A, Klein, R S, Chaganti
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Conservation genetics in transition to conservation genomics
Trends in Genetics, 2010Over the past twenty years conservation genetics has progressed from being mainly a theory-based field of population biology to a full-grown empirical discipline. Technological developments in molecular genetics have led to extensive use of neutral molecular markers such as microsatellites in conservation biology.
Ouborg, N. Joop +4 more
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Genetic Associations of Transitional Cell Carcinoma
British Journal of Urology, 1979Summary– A series of 101 cases of transitional cell carcinoma (TCC) was contrasted with a control series for several genetic parameters. Three genetic associations were demonstrated with the TCC patients having A gene frequencies, HLA B5 and HLA CW4 genes all higher than might be expected by chance.
D W, Herring +2 more
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Genetic Dissection of the Permeability Transition Pore
Journal of Bioenergetics and Biomembranes, 2005The permeability transition pore (PTP) regulates the structural re-organization of mitochondria in response to changes in cellular Ca(2+) and is thought to be an important participant in mitochondrial responses to cell death signals. Although the proteins forming the PTP have yet to be rigorously identified, recent examination of the response of ...
BERNARDI, PAOLO, FORTE M.
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Molecular genetic aspects of prostate transition zone lesions
Urology, 2003The prostate is a composite exocrine gland divided into four zones: anterior fibromuscular stroma, peripheral zone (PZ), central zone, and preprostatic tissue. The preprostatic tissue is the smallest, but most complex, prostate zone. Its main component is a cylindrical, smooth, muscular sphincter. Inside this muscle, are tiny periurethral glands.
Jasminka, Pavelić +2 more
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Genetic algorithm based transition probabilities estimation
2017 13th IEEE Conference on Automation Science and Engineering (CASE), 2017Renal transplantation is the best treatment for end-stage renal disease. Transplanted patients need to take immunosuppressant drugs to keep long-term survival. However, the cost of immunosuppressant drugs is high in China, so it is necessary to conduct a cost-effectiveness analysis of immunosuppressant drugs to provide guidance for medical decision ...
Xiuxian Wang +3 more
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Genetically transitional disease: a new concept in genomic medicine
Trends in Genetics, 2023Traditional classification of genetic diseases as monogenic and polygenic has lagged far behind scientific progress. In this opinion article, we propose and define a new terminology, genetically transitional disease (GTD), referring to cases where a large-effect mutation is necessary, but not sufficient, to cause disease.
Qingping Yao +3 more
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Urology, 1999
Multifocality of transitional cell carcinoma (TCC) has been attributed to seeding of exfoliated tumor cells or to a general sensitivity of the entire urothelium to carcinogenic stimuli. By contrast, TCC has been shown to evolve as a consequence of genetic defects and chromosomal instability.
A, Pycha +6 more
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Multifocality of transitional cell carcinoma (TCC) has been attributed to seeding of exfoliated tumor cells or to a general sensitivity of the entire urothelium to carcinogenic stimuli. By contrast, TCC has been shown to evolve as a consequence of genetic defects and chromosomal instability.
A, Pycha +6 more
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