Temporal transcriptome analysis reveals the two-phase action of florigens in rice flowering. [PDF]
Sun R+4 more
europepmc +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source
scDown: A Pipeline for Single-Cell RNA-Seq Downstream Analysis. [PDF]
Sun L+7 more
europepmc +1 more source
Institute on Disability / UCED Scholarly Activity & Involvement: July 1, 2013 – June 30, 2014 [PDF]
Drum, Charles E.
core +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Pharmacogenomic Testing in the Clinical Laboratory: Historical Progress and Future Opportunities. [PDF]
Moyer AM, Black JL.
europepmc +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
NF-κB-mediated developmental delay extends lifespan in <i>Drosophila</i>. [PDF]
Kang P+17 more
europepmc +1 more source
Reassessing the mitochondrial DNA evidence for migration at the Mesolithic–Neolithic transition [PDF]
Bonsall, Clive+2 more
core
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley +1 more source