Decoupled maternal and zygotic genetic effects shape the evolution of development
Evolutionary transitions from indirect to direct development involve changes in both maternal and zygotic genetic factors, with distinctive population-genetic implications, but empirical data on the genetics of such transitions are lacking.
Christina Zakas +3 more
doaj +1 more source
COVID-19 2022 update: transition of the pandemic to the endemic phase
COVID-19, which is caused by the SARS-CoV-2, has ravaged the world for the past 2 years. Here, we review the current state of research into the disease with focus on its history, human genetics and genomics and the transition from the pandemic to the ...
Michela Biancolella +6 more
doaj +1 more source
Genetic interactions that promote the floral transition inArabidopsis [PDF]
The transition from vegetative to reproductive development is marked by the establishment of the floral developmental program in the lateral primordia formed by the shoot apical meristem. This is achieved by the coordinate activation, in these primordia, of a set of genes that regulate floral initiation.
Madueño, F. +3 more
openaire +4 more sources
Singular limit of an activator-inhibitor type model
We consider a reaction-diffusion system of activator-inhibitor type arising in the theory of phase transition. Itappears in biological contexts such as pattern formation in population genetics.
Marie Henry
doaj +1 more source
The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature [PDF]
In vertebrates, body musculature originates from somites, whereas head muscles originate from the cranial mesoderm. Neck muscles are located in the transition between these regions.
Christ, B. +9 more
core +1 more source
Understanding the biology of urothelial cancer metastasis
Management of unresectable urothelial cancer (UC) has been a clinical challenge for decades. While drug resistance is a key issue, precise understanding of biology of UC metastasis is another challenge for the improvement of treatment outcome of UC ...
Takashi Kobayashi
doaj +1 more source
Molecular Genetics of Intracranial Meningiomas with Emphasis on Canonical Wnt Signalling. [PDF]
Research over the last decade recognized the importance of novel molecular pathways in pathogenesis of intracranial meningiomas. In this review, we focus on human brain tumours meningiomas and the involvement of Wnt signalling pathway genes and proteins ...
Kafka, Anja +2 more
core +2 more sources
Genetics of a de novo origin of undifferentiated multicellularity [PDF]
The evolution of multicellularity was a major transition in evolution and set the stage for unprecedented increases in complexity, especially in land plants and animals.
Matthew D. Herron +3 more
doaj +1 more source
Genetic conditions of short stature: A review of three classic examples
Noonan, Turner, and Prader-Willi syndromes are classical genetic disorders that are marked by short stature. Each disorder has been recognized for several decades and is backed by extensive published literature describing its features, genetic origins ...
Merlin G. Butler +12 more
doaj +1 more source
Simulation from endpoint-conditioned, continuous-time Markov chains on a finite state space, with applications to molecular evolution [PDF]
Analyses of serially-sampled data often begin with the assumption that the observations represent discrete samples from a latent continuous-time stochastic process.
Hobolth, Asger, Stone, Eric A.
core +1 more source

