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The corn smut fungus Ustilago maydis serves as a model species for studying fungal dimorphism and its role in phytopathogenic development. The pathogen has two growth phases: a saprobic yeast phase and a pathogenic filamentous phase. Dimorphic transition
Teeratas Kijpornyongpan +1 more
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Network for Therapy in Rare Epilepsies (NETRE): Lessons From the Past 15 Years
Background: In 2005, Network for Therapy in Rare Epilepsies (NETRE)—was initiated in order to share treatment experiences among clinicians in patients with rare epilepsies. Here we describe the structure of the rapidly growing NETRE and summarize some of
Celina von Stülpnagel +21 more
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The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortia: design, results and future prospects [PDF]
The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease.
Alina Rodriguez (17166361) +6 more
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Forecasting emergence of COVID-19 variants of concern
We consider whether one can forecast the emergence of variants of concern in the SARS-CoV-2 outbreak and similar pandemics. We explore methods of population genetics and identify key relevant principles in both deterministic and stochastic models of ...
James Kyle Miller +2 more
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Genetic interactions that promote the floral transition inArabidopsis [PDF]
The transition from vegetative to reproductive development is marked by the establishment of the floral developmental program in the lateral primordia formed by the shoot apical meristem. This is achieved by the coordinate activation, in these primordia, of a set of genes that regulate floral initiation.
Madueño, F. +3 more
openaire +4 more sources
Timely Control of Gastrointestinal Eubiosis: A Strategic Pillar of Pig Health
The pig gastrointestinal tract (GIT) is an open ecosystem in which microorganisms and their host are mutually involved and continually adapt to different factors and problems which may or may not be host dependent or due to the production system. The aim
Paolo Trevisi +3 more
doaj +1 more source
Decoupled maternal and zygotic genetic effects shape the evolution of development
Evolutionary transitions from indirect to direct development involve changes in both maternal and zygotic genetic factors, with distinctive population-genetic implications, but empirical data on the genetics of such transitions are lacking.
Christina Zakas +3 more
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COVID-19 2022 update: transition of the pandemic to the endemic phase
COVID-19, which is caused by the SARS-CoV-2, has ravaged the world for the past 2 years. Here, we review the current state of research into the disease with focus on its history, human genetics and genomics and the transition from the pandemic to the ...
Michela Biancolella +6 more
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Transitioning from Forensic Genetics to Forensic Genomics [PDF]
Due to its support of law enforcement, forensics is a conservative field; nevertheless, driven by scientific and technological progress, forensic genetics is slowly transitioning into forensic genomics. With this Special Issue of Genes we acknowledge and appreciate this rather recent development by not only introducing the field of forensics to the ...
Manfred Kayser, Walther Parson
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Understanding the biology of urothelial cancer metastasis
Management of unresectable urothelial cancer (UC) has been a clinical challenge for decades. While drug resistance is a key issue, precise understanding of biology of UC metastasis is another challenge for the improvement of treatment outcome of UC ...
Takashi Kobayashi
doaj +1 more source

