Results 51 to 60 of about 172,050 (245)

Psychiatric neuroimaging at a crossroads: Insights from psychiatric genetics

Developmental Cognitive Neuroscience
Thanks to methodological advances, large-scale data collections, and longitudinal designs, psychiatric neuroimaging is better equipped than ever to identify the neurobiological underpinnings of youth mental health problems.
Lorenza Dall’Aglio, Saúl Urbina Johanson, Travis Mallard, Sander Lamballais, Scott Delaney, Jordan W. Smoller, Ryan L. Muetzel, Henning Tiemeier   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Modeling the transition from acute to chronic postsurgical pain in youth: A narrative review of epidemiologic, perioperative, and psychosocial factors

Canadian Journal of Pain, 2022
A growing number of studies have identified high rates of pediatric chronic postsurgical pain (CPSP) after major surgery. Pediatric CPSP is associated with pain-related distress and comorbid mental health outcomes, such as anxiety and depression.
Brittany N. Rosenbloom, Joel Katz
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Anthocyanin contents and molecular changes in rose petals during the post-anthesis color transition

Ornamental Plant Research
Flower color transitions during anthesis are taxonomically widespread; however, the mechanisms underlying post-anthesis color transition in roses are unclear.
Ying Kong, Huan Wang, Li Qiu, Xiaoying Dou, Lixin Lang, Jinrong Bai   +5 more
doaj   +1 more source

Simulation of Ultrafast Optical Transitions using Genetic Algorithm

Nonlinear Analysis: Modelling and Control, 2001
The purpose of this paper is to investigate the possibility of application of the genetic algorithm to quantum control of electronic transitions between energy bands in solids. In particular, the hole transitions between valence bands induced by ultrashort (femtosecond duration) electric field pulse will be considered.
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Genetic instability and transitional cell carcinoma of the bladder

BJU International, 2003
The development of cancer occurs in a stepwise fashion, with each step representing the mutation in one of several key genes. However, the mutation rate of somatic cells is too low to account for the number of mutations required for a cell to undergo carcinogenesis.
Catto, J, Meuth, M, Hamdy, F
openaire   +2 more sources