Results 51 to 60 of about 480,980 (318)
The (r)evolution of cancer genetics
BMC Biology, 2010 The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation.
Ciccarelli Francesca D
doaj +1 more source
The formation of cancer stem cells in EMT6/Ro tumor: Hybrid modeling within its micro-environment
Informatics in Medicine Unlocked, 2020 We investigate the formation of cancer stem cells and their role in maintaining avascular solid tumors. For this purpose, we provide a mathematical framework to study the major biological interpretations on the stemness of cancerous cells (stochastic ...
Armin Pirastehzad +2 more
doaj +1 more source
Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus +6 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed +5 more
wiley +1 more source
From rat pathophysiology to genomic medicine: an interview with Howard Jacob
Disease Models & Mechanisms, 2016 Howard Jacob is best known for pioneering genomic sequencing of a patient to solve a mysterious pediatric case in 2010. With roots in pharmacology and cardiovascular disease, however, his career has largely been dedicated to dissecting the physiology and
doaj +1 more source
Frontiers in Oncology, 2021 Lung cancer is the leading cause of cancer-related deaths and is the primary source of brain metastases. Despite great advances in the study of the genetics and etiology of lung cancer in previous decades, the identification of the factors and mechanisms
Xu-Ge Wei, Ke-Wei Bi, Bo Li
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Computational inference beyond Kingman's coalescent [PDF]
, 2015 Full likelihood inference under Kingman's coalescent is a computationally challenging problem to which importance sampling (IS) and the product of approximate conditionals (PAC) method have been applied successfully.
Jenkins, Paul +2 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn +4 more
wiley +1 more source
Inhibitory effects of knocking down homeobox C8 on seven factors-induced somatic cell reprogramming
浙江大学学报. 农业与生命科学版, 2022 To explore the mechanism of seven factors (Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Esrrb-Sall4)-induced somatic cell reprogramming, we analyzed the related role of homeobox C8 (Hoxc8) in the process of pluripotency network reconstruction through forward and reverse
HUANG Yi +5 more
doaj +1 more source
A Genetic Study on Lumbosacral Transitional Vertebra.
Orthopedics & Traumatology, 1991 Various studies have placed the prevalence of lumbosacral transitional vertebra to be anywhere from 0.6 to 25% of the general population.We found twenty cases of the transitional vertebra. They had a high frequency (64.2%) of the anomaly. There may be a genetic factor involved in the lumbosacral transitional vertebra.
Hideki Sonoda +8 more
openaire +2 more sources