Results 51 to 60 of about 480,286 (292)
THE NEOLITHIC TRANSITION AND THE GENETICS OF POPULATIONS IN EUROPE: A REVIEW [PDF]
Evolution, 1986 Peer Reviewed ; https://deepblue.lib.umich.edu/bitstream/2027.42/137425/1/evo00491 ...
openaire +3 more sources
From Genetics to Genomics of Epilepsy
Neurology Research International, 2012 The introduction of DNA microarrays and DNA sequencing technologies in medical genetics and diagnostics has been a challenge that has significantly transformed medical practice and patient management.
Silvio Garofalo +2 more
doaj +1 more source
Currently Clinical Views on Genetics of Wilson′s Disease
Chinese Medical Journal, 2015 Objective: The objective of this study was to review the research on clinical genetics of Wilson′s disease (WD). Data Sources: We searched documents from PubMed and Wanfang databases both in English and Chinese up to 2014 using the keywords WD in ...
Chen Chen +5 more
doaj +1 more source
The (r)evolution of cancer genetics
BMC Biology, 2010 The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation.
Ciccarelli Francesca D
doaj +1 more source
The formation of cancer stem cells in EMT6/Ro tumor: Hybrid modeling within its micro-environment
Informatics in Medicine Unlocked, 2020 We investigate the formation of cancer stem cells and their role in maintaining avascular solid tumors. For this purpose, we provide a mathematical framework to study the major biological interpretations on the stemness of cancerous cells (stochastic ...
Armin Pirastehzad +2 more
doaj +1 more source
Mutation in Populations Governed by a Galton-Watson Branching Process
, 2018 A population genetics model based on a multitype branching process, or equivalently a Galton-Watson branching process for multiple alleles, is pre- sented. The diffusion limit forward Kolmogorov equation is derived for the case of neutral mutations.
Burden, Conrad J., Wei, Yi
core +1 more source
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
An Evolutionary Reduction Principle for Mutation Rates at Multiple Loci [PDF]
, 2010 A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of multilocus event
A. Eyre-Walker +60 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine +14 more
wiley +1 more source
Genetic instability and transitional cell carcinoma of the bladder
BJU International, 2003 The development of cancer occurs in a stepwise fashion, with each step representing the mutation in one of several key genes. However, the mutation rate of somatic cells is too low to account for the number of mutations required for a cell to undergo carcinogenesis.
Catto, J, Meuth, M, Hamdy, F
openaire +2 more sources