Results 41 to 50 of about 2,256,393 (304)
Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
Pediatric Blood &Cancer, EarlyView.ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
Fostering energy efficiency dynamics through ex-ante strategic niche management: the UK perspective [PDF]
, 2013 The United Kingdom building sector has been challenged to retrofit a huge stock of existing buildings in order to increase its adaptive capacity for climate change impacts.
Goulding, Jack Steven +2 more
core
Transition skills in citizens communities
Oñati Socio-Legal SeriesIn a context of demographic, digital and ecological transitions, the promotion of citizen participation in the design of public policies is increasingly in demand and relevant.
Javier Castro-Spila +2 more
doaj +1 more source
Transitions in Theory and Practice: Managing Metals in the Circular Economy
Resources, 2014 Transitioning from current resource management practice dominated by linear economic models of consumption and production, to circular models of resource use, will require insights into the stages and processes associated with socio-technical transitions.
Melissa Jackson +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song +15 more
wiley +1 more source
Ecology and Society, 2014 Faced with numerous seemingly intractable social and environmental challenges, many scholars and practitioners are increasingly interested in understanding how to actively engage and transform the existing systems holding such problems in place ...
Michele-Lee Moore +8 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
From "community" to "commercial" FLOSS: The case of moodle [PDF]
, 2010 This is the post-print version of the final published article that is available from the link below. Copyright © 2010 ACM, Inc.This paper documents the evolution of Moodle, an advanced Content Management System, and its transition from a purely volunteer-
Baravalle, A, Capiluppi, A, Heap, NW
core +1 more source
Towards a Sustainable i-City: Intelligent Transition Management of Digital Places
Kvalita Inovácia Prosperita, 2017 Modern cities operate in a force field of great challenges. The introduction of digital technology may facilitate the necessary transition management of cities but calls also for a new and intelligent use of a wealth of information for coping with great
Karima Kourtit
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source