Results 61 to 70 of about 10,997,848 (299)
Conceptualizing, Observing, and Influencing Social-Ecological Transitions
This article creates a meeting ground between two distinct and fairly elaborate research traditions dealing with social "transitions": the Dutch societal transitions management approach, and the Viennese sociometabolic transitions approach.
Marina Fischer-Kowalski, Jan Rotmans
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Background: In Mecklenburg-Western Pomerania, multidisciplinary round tables bring together stakeholders from the healthcare sector to jointly develop and advance solutions for regional care challenges on a semi-annual basis.
Jann Niklas Vogel +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Managing the twin transition: Organizational design and People Management
reservedIn the current era of rapid technological advancements and growing environmental concerns, organizations face the challenge of navigating the twin transition.
CARRARO, MARCO
core
Numerical Study of the Effect of Freestream Turbulence on by-pass Transition in a Boundary Layer [PDF]
We use direct numerical simulations in the presence of free-stream turbulence having different values of intensity, T u, and integral length scale, L, in order to determine which kind of structures are involved in the path to transition of a boundary ...
Robinet, Jean Christophe +3 more
core +1 more source
Over the past ten years, the member institutions of the Austrian Academic Library Consortium (KEMÖ) have gradually opened up their researchers’ publications to the world, one publisher at a time.
Rita Pinhasi, Brigitte Kromp
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
As Lao PDR prepares to graduate from Least Developed Country (LDC) status by 2020 to become an upper-middle-income country by 2030, it also expects to face declining funding from external sources and the need to increase domestic financing for health.
openaire +3 more sources
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source

