Results 61 to 70 of about 10,997,848 (299)

Conceptualizing, Observing, and Influencing Social-Ecological Transitions

open access: yesEcology and Society, 2009
This article creates a meeting ground between two distinct and fairly elaborate research traditions dealing with social "transitions": the Dutch societal transitions management approach, and the Viennese sociometabolic transitions approach.
Marina Fischer-Kowalski, Jan Rotmans
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From bottleneck to efficiency: Key areas for improving discharge management in healthcare – a qualitative study

open access: yesGMS German Medical Science
Background: In Mecklenburg-Western Pomerania, multidisciplinary round tables bring together stakeholders from the healthcare sector to jointly develop and advance solutions for regional care challenges on a semi-annual basis.
Jann Niklas Vogel   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Managing the twin transition: Organizational design and People Management

open access: yes, 2023
reservedIn the current era of rapid technological advancements and growing environmental concerns, organizations face the challenge of navigating the twin transition.
CARRARO, MARCO
core  

Numerical Study of the Effect of Freestream Turbulence on by-pass Transition in a Boundary Layer [PDF]

open access: yes, 2014
We use direct numerical simulations in the presence of free-stream turbulence having different values of intensity, T u, and integral length scale, L, in order to determine which kind of structures are involved in the path to transition of a boundary ...
Robinet, Jean Christophe   +3 more
core   +1 more source

Preparing institutions for the transition: consortial cost-sharing models in transformative agreements in Austria

open access: yesInsights: The UKSG Journal
Over the past ten years, the member institutions of the Austrian Academic Library Consortium (KEMÖ) have gradually opened up their researchers’ publications to the world, one publisher at a time.
Rita Pinhasi, Brigitte Kromp
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Managing Transitions

open access: yes, 2017
As Lao PDR prepares to graduate from Least Developed Country (LDC) status by 2020 to become an upper-middle-income country by 2030, it also expects to face declining funding from external sources and the need to increase domestic financing for health.
openaire   +3 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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