Results 71 to 80 of about 10,997,848 (299)

Translating Transitions Thinking and Transition Management into the City Planning World.

, 2018
City planning draws out relationships between land use patterns, housing form and density, transport, energy provision and other infrastructures. While commonly struggling with the task, a city’s planning system could be one of the key integrating forces
Peter Walsh, Walsh, P
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Transition Management

, 2004
«Challenges to Collective Security» Working Papers from NUPI’s UN Programme: The emerging consensus on the need to establish more effective United Nations mechanisms for managing the transition from conflict to peace, and on the importance of addressing the nexus between development and security, is not sufficiently reflected in the organisational ...
openaire   +3 more sources

Managing Transitions for Sustainable Development [PDF]

, 2006
textabstractThe challenge of sustainable development presents our society with the need for longterm, structural changes or transitions in sectors such as energy-supply, mobility, agriculture and health-care. Based on a multi-phase and multi-level framework for transitions, we ask whether managing transitions is possible and then outline an operational
Loorbach, Derk, Rotmans, Jan
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Project management offices in transition

, 2010
This paper presents empirical results from a research on Project Management Offices (PMO) in transition. While PMOs are now a prominentfeature of organizational project management, the underlying logic that leads to their implementation or renewal is ...
Müller, Ralf,, Tomas Blomquist, Brian Hobbs, Monique Aubry, Blomquist, Tomas,, Ralf Müller, Aubry, Monique,, Hobbs, Brian,   +7 more
core   +1 more source

Viewpoint planning with transition management for active object recognition. [PDF]

Front Neurorobot, 2023
Sun H, Zhu F, Li Y, Zhao P, Kong Y, Wang J, Wan Y, Fu S.   +7 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A Transition For All: Equity and community engagement in the transition of water supply management to utilities in refugee settlements in Uganda

, 2020
Water supply schemes in refugee settlements in Uganda are being transitioned from management by humanitarian actors to management by national and regional utilities in an effort to improve their long-term sustainability.
Allen, John, Muturi, Caroline
core   +1 more source