Results 21 to 30 of about 561,665 (262)
pygtm : a python Geospatial Transition Matrix toolbox
The Geospatial Transition Matrix toolbox allows the creation of a transition matrix, representing a Markov Chain of the dynamics, from a set of trajectories.
Luzie Helfmann, Philippe Miron
core +1 more source
Calculation of LTC Premiums based on direct estimates of transition probabilities [PDF]
In this paper we model the life-history of LTC patients using a Markovian multi-state model in order to calculate premiums for a given LTC-plan. Instead of estimating the transition intensities in this model we use the approach suggested by Andersen et ...
Helms, F. +3 more
core +1 more source
To overcome the tradeoff between strength and ductility of materials and obtain titanium matrix composites with excellent mechanical properties, in this study, the in situ-synthesized TiC particles and Ti-Al-V-Mo-Cr (Ti1400) alloy-reinforced Ti6Al4V (TC4)
Mingjia Li +6 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Multicritical matrix models and the chiral phase transition
Universality of multicritical unitary matrix models is shown and a new scaling behavior is found in the microscopic region of the spectrum, which may be relevant for the low energy spectrum of the Dirac operator at the chiral phase ...
Akemann, G, Akemann, Gernot, G. Akemann
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Transition matrix (a) for normal cases (b) for abnormal cases (c) average transition matrix TMavg (d) net transition matrix TMnet (e) binary neighborhood matrix NM (e) conditioned net transition matrix TMc.
Jayanthi Sivaswamy (5983034) +2 more
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source

