Results 81 to 90 of about 597,070 (307)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A tight-binding potential for atomistic simulations of carbon interacting with transition metals: Application to the Ni-C system [PDF]

, 2008
We present a tight-binding potential for transition metals, carbon, and transition metal carbides, which has been optimized through a systematic fitting procedure.
A. Cottrell, C. Bichara, Ch. Kittel, Ch.-H. de Novion, D. G. Pettifor, F. Ducastelle, F. Ducastelle, F. Ducastelle, H. Amara, H. J. Grabke, J. Friedel, J.-M. Roussel, J.-P. Gaspard, J.-P. Landesman, L. E. Toth, M. I. Heggie, N. Eustathopoulos, O. K. Andersen, P. Turchi, V. A. Gubanov, W. H. Press   +20 more
core   +6 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

The influence of transition metal solutes on dislocation core structure and values of Peierls stress and barrier in tungsten

, 2012
Several transition metals were examined to evaluate their potential for improving the ductility of tungsten. The dislocation core structure and Peierls stress and barrier of $1/2$ screw dislocations in binary tungsten-transition metal alloys (W$_{1-x}$TM$
Edington J W Gilbert A Klein M J, El-Guebaly L, G D Samolyuk, Garfinkle M, Geach J C Hughes J E, Giannozzi P, Gröger R, Gröger R Vitek V, Hirth J, Klopp W D, Kurdyumova G G, Lassner E, Massalski T B, Nabarro F R N, O’Dell S McKechnie T Shchetkovskiy A Smirnov A, R E Stoller, Savitskii E M, Trefilov V I, Vitek V, Y N Osetsky   +19 more
core   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Orbital-selective Mott transitions: Heavy fermions and beyond

, 2010
Quantum phase transitions in metals are often accompanied by violations of Fermi liquid behavior in the quantum critical regime. Particularly fascinating are transitions beyond the Landau-Ginzburg-Wilson concept of a local order parameter.
A. Abanov, A. Benlagra, A. Casey, A. Hackl, A. Hackl, A. Koga, A. Liebsch, A. Liebsch, A. Rosch, A. Rüegg, A. Schröder, A. Schröder, A.C. Hewson, A.J. Millis, B.L. Altshuler, C. Knecht, C. Pépin, C. Pépin, C.P. Nave, D. Belitz, D.R. Grempel, D.S. Greywall, D.V. Efremov, E. Fradkin, E.W. Carlson, G. Baym, G. Knebel, G. Misguich, G. Zwicknagl, G. Zwicknagl, G. Zwicknagl, G.R. Stewart, G.R. Stewart, H. Ishida, H. Löhneysen v., H. Löhneysen v., H. Löhneysen v., H. Löhneysen v., H. Shishido, H. Watanabe, H. Wilhelm, I. Paul, I. Paul, I. Paul, J. Custers, J. Wu, J.-X. Zhu, J.-X. Zhu, J.A. Hertz, K. Haule, K.-S. Kim, K.-S. Kim, K.-S. Kim, K.-S. Kim, L. Dell’Anna, L. Leo De, L. Leo De, L. Medici de, L. Medici de, L. Medici de, L. Zhu, L.B. Ioffe, L.C. Martin, M. Ferrero, M. Neumann, M. Neupane, M. Oshikawa, M. Roger, M. Rotter, M. Siqueira, M. Vojta, M. Vojta, M.T. Glossop, M.Yu. Reizer, Matthias Vojta, N. Lanata, N. Nagaosa, N.K. Sato, O. Stockert, O. Trovarelli, P. Coleman, P. Coleman, P. Coleman, P. Gegenwart, P. Gegenwart, P. Gegenwart, P. Sun, P. Werner, P. Werner, P.A. Lee, P.A. Lee, P.A. Lee, Q. Si, Q. Si, Q. Si, Q. Si, R. Arita, R. Küchler, R. Moessner, S. Biermann, S. Burdin, S. Doniach, S. Friedemann, S. Nakatsuji, S. Paschen, S. Sachdev, S. Sachdev, S. Sachdev, S. Sakai, S.-P. Kou, S.J. Yamamoto, S.K. Goh, T. Holstein, T. Moriya, T. Moriya, T. Park, T. Park, T. Senthil, T. Senthil, T. Senthil, T. Senthil, T. Senthil, T. Senthil, T. Senthil, T. Vojta, T.A. Costi, V. Anisimov, Y. Kamihara   +127 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Preparation Process and Performance Analysis of Oxygen-containing Coating on Transition Metal

Yuanzineng kexue jishu
As candidate materials for the collector in thermionic energy converters (TECs), reducing the surface work function of transition metals can lower the barrier index between TEC electrodes, thereby improving their thermoelectric conversion efficiency and ...
MA Ru, ZHONG Wuye, JIN Rui, REN Siqi, YAO Siyu, QI Lijun
doaj   +1 more source