Results 141 to 150 of about 16,913,600 (335)

Editorial: Strategies for mitigating the transition period stress in dairy cattle

Frontiers in Veterinary Science, 2023
Mohanned Naif Alhussien, Ajay Kumar Dang, Dengpan Bu   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Inflation in Estonia : The effect of transition [PDF]

, 1995
Uudelleenjulkaistu pdf-muodossa 2002 (Idäntalouksien yksikön sarja)Reprint in PDF format 2002 (Unit for Eastern European Economies series)This paper treats inflation in Estonia during a period of dramatic change.In the course of this period both the ...
Sepp, Urmas
core  

Integrative Insights into Metabolic, Oxidative, and Immune Adaptations During the Transition Period in Dairy Cows: Revisiting Nutritional Strategies and Emerging Roles of Injectable Trace Minerals

Dairy
The transition period, spanning approximately three weeks before and after parturition, represents one of the most critical physiological windows in dairy production.
Mohammad Javed Ashar, Paula A. Gonzalez-Rivas, Frank R. Dunshea, Christina D. Marth, Surinder S. Chauhan   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Cities in Transition [PDF]

Cities in transition face a unique set of challenges that came forth due to interplay of the legacy of socialist urban policies and transition to the market economy.
Oleksandr Shepotylo
core  

Functional and transcriptomic profiling of bovine circulating neutrophils during in vitro lipopolysaccharide challenge across different energetic states

Journal of Dairy Science
: Polymorphonuclear leukocytes are pivotal players in the innate immune response of dairy cows. Their functionality (phagocytosis [PC] and oxidative burst [OB]) and gene expression patterns, however, can be modulated by varying energetic conditions ...
Lei Xie, Sanjana Malledevarahalli Chandrappa, Sebastian Gonzalez Andueza, Hafez Sadeghi, Priit Karis, Muhammad Hussnain Rashid, Mehrnaz Niazi, Yuan Fan, Kaixi Qiao, Qiang Dong, Alessandro Ricci, Geert Opsomer, Osvaldo Bogado Pascottini   +12 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Tempo-Adjusted Period Parity Progression Measures: [PDF]

In this paper we apply tempo-adjusted period parity progression ratios (Kohler and Ortega 2002) to Sweden, the Netherlands and Spain. These countries represent three distinct demographic patterns in contemporary Europe and are of particular interest for ...
Hans-Peter Kohler, José Antonio Ortega
core  

Precalving nutritional factors associated with colostrum quality and yield in Québec dairy herds

Journal of Dairy Science
: The objective of this prospective longitudinal study was to identify precalving dietary ingredients, nutrient composition, cow characteristics, and herd management affecting colostral Ig G concentration, Brix values, and yield of multiparous Holstein ...
K. Dubois, C. Côrtes, S. Buczinski, M. Duplessis   +3 more
doaj   +1 more source