Results 91 to 100 of about 2,386,679 (302)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

The Nodal Boundary Condition Method : Wave Functions and Transition Probabilities for Atoms with Two Valence Electrons [PDF]

open access: yes, 1963
A method is presented for computing valence atomic wave functions and transition probabilities. This method, called the "nodal boundary condition method", is a modified self-consistent-field approach to eliminate the need for calculating wave functions ...
Helliwell, Thomas McCalfree
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Theoretical Studies on Transition Wavelengths and Transition Probabilities [PDF]

open access: yesInternational Astronomical Union Colloquium, 1972
A discussion is presented of some theoretical methods for predicting atomic transition wavelengths and transition probabilities that are especially useful for highly stripped ions. Particular attention is given to procedures involving model potentials and pseudo-potentials and to procedures involving expansions in inverse powers of the nuclear charge ...
openaire   +1 more source

Transition Probabilities by Age, Gender and Education.

open access: yes, 2015
(A) Transition probabilities from active to functional disability. (B) Transition probabilities from functional disability to active. (C) Transition probabilities from active to death. (D) Transition probabilities from functional disability to death.
Chi-Tsun Chiu (738907)   +6 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Modelling Low Pay Transition Probabilities, Accounting for Panel Attrition, Non-Response, and Initial Conditions [PDF]

open access: yes
We model annual low pay transition probabilities taking account of three potentially endogenous selections: two sample drop-out mechanisms (panel attrition, non-employment) and ‘initial conditions’ (base-year low pay status).
Lorenzo Cappellari, Stephen P. Jenkins
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Country Default Probabilities: Assessing and Backtesting [PDF]

open access: yes
We address the problem how to estimate default probabilities for sovereign countries based on market data of traded debt. A structural Merton-type model is applied to a sample of emerging market and transition countries.
Vogl, Konstantin   +3 more
core  

Plot of transition probabilities.

open access: yes, 2016
Plot of transition probabilities.
Andrea Icks (282944)   +3 more
core   +1 more source

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