Results 81 to 90 of about 347,812 (276)
Diabetes Experiences of Transition from Childhood to Adulthood Care
Florence Nightingale Journal of Nursing, 2022 Alireza Nikbakht Nasrabadi +1 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Navigating the teen years: promise and peril for northern New Hampshire youth [PDF]
, 2009 This report provides a snapshot of how youth are doing in Carroll, Coos, and Grafton counties and describes some of the difficulties they and their communities face as they negotiate the transition to adulthood.
Shattuck, Anne M.
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Financing Entrepreneurship Programs for Youth Transitioning Out of Foster Care [PDF]
, 2007 This publication is one of a series of briefs exploring strategies for financing supports and services that help youth in foster care make successful transitions to adulthood. The Finance Project produced this brief with support from the Foster Care Work
Barbara Hanson Langford +2 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Choices, Challenges, and Options: Child SSI Recipients Preparing for the Transition to Adult Life [PDF]
, 2005 For young people receiving Supplemental Security Income (SSI), a means-tested cash benefit for children with disabilities, the transition into young adulthood is complicated for several reasons.
David Wittenburg, Pamela J. Loprest
core
The time benefits of young adult home stayers in France and Italy: a new perspective on the transition to adulthood? [PDF]
, 2017 This article analyses how two co-residing generations contribute to the housework workload in Italy and France during the early 2000s. It studies the intergenerational exchange of time between young adults and their parents by indirectly comparing the ...
Mencarini, Letizia +3 more
core +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source