Results 41 to 50 of about 1,182,569 (302)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Key features of normal ECG in children
Медицинский совет, 2013 The article is devoted to current views on the ECG diagnosis in pediatrics. The group of authors considered some of the most characteristic changes in ECG in children.
V. S. Zadionchenko +3 more
doaj +1 more source
On red shifs in the transition region and corona
, 2010 We present evidence that transition region red-shifts are naturally produced in episodically heated models where the average volumetric heating scale height lies between that of the chromospheric pressure scale height of 200 km and the coronal scale ...
B. De Pontieu +22 more
core +1 more source
Superfluid-Insulator transition of ultracold atoms in an optical lattice in the presence of a synthetic magnetic field [PDF]
, 2010 We study the Mott insulator-superfluid transition of ultracold bosonic atoms in a two-dimensional square optical lattice in the presence of a synthetic magnetic field with p/q (p and q being co-prime integers) flux quanta passing through each lattice ...
Jaksch D. +7 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A new solution to the solar neutrino deficit
, 2002 We reexamine the transition magnetic moment solution to the solar neutrino problem. We argue that the absence of large time variations in the Super-Kamiokande rate provides strong evidence against spin-flavor flip in the solar convective zone.
Ahmad +43 more
core +1 more source
Hot mantle upwelling across the 660 beneath Yellowstone [PDF]
, 2012 P-to-s receiver functions mapped to depth through P and S body-wave tomography models image continuous 410 and 660 km discontinuities beneath the area covered by USArray prior to the year 2011. Mean depths to the 410 and 660 km discontinuities of 410 and
Dueker, Kenneth +3 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Remote Sensing, 2021 This paper examines cloud-related variations of atmospheric aerosols that occur in partly cloudy regions containing low-altitude clouds. The goal is to better understand aerosol behaviors and to help better represent the radiative effects of aerosols on ...
Tamás Várnai, Alexander Marshak
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source