Results 171 to 180 of about 5,409,033 (241)

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

Expression profiles and clinical significance of cystatin family genes in transitional cell carcinoma of the urinary bladder. [PDF]

Bladder (San Franc)
Xu H, Liu W, Kuang X, Zhao J, Wang X, Li B.   +5 more
europepmc   +1 more source

Survey of Mast Cell Density in Transitional Cell Carcinoma. [PDF]

Iran J Pathol, 2021
Moradi Tabriz H, Obohat M, Vahedifard F, Eftekharjavadi A.   +3 more
europepmc   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Uncommon presentation of transitional cell carcinoma: A case report of hand involvement. [PDF]

Clin Case Rep
Sanei-Far Z, Gharib M.
europepmc   +1 more source

Expression of proto-oncogene c-Myc in patients with urinary bladder transitional cell carcinoma. [PDF]

Curr Urol, 2021
Fragkoulis C, Ntoumas G, Glykas I, Papadopoulos G, Stathouros G, Kostopoulou A, Choreftaki T, Ntoumas K.   +7 more
europepmc   +1 more source

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin, Yao Xiao, Shuangzi Luo, Yifan Li, Wenfei Zhang, Xiaoyu Zhang, Xinyi Wang, Di Wu, Jieru Hong, Yongkun Luan, Xun Huang, Yixiu Wang, Ningbo Wu, Xiaoxiao Hu, Fei Zhao, Wei Li, Xiao Luo, Bi Shi   +17 more
wiley   +1 more source

Bilateral nephrolithiasis and upper tract transitional cell carcinoma in horseshoe kidney. [PDF]

Curr Urol
Gaines JM, Macdonald EJ, Rai A, Hoenig D, Smith A, Okeke Z, Aro T.   +6 more
europepmc   +1 more source

Establishment and Characterization of FusionRed Stable Transfected Canine Prostate Adenocarcinoma and Transitional Cell Carcinoma Cells. [PDF]

In Vivo, 2022
Alnajjar S, Nolte I, Schille JT, Sender S, Trakoolju N, Perez SV, Zechner D, Vollmar B, Junghanss C, Murua Escobar H.   +9 more
europepmc   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source