Results 241 to 250 of about 72,739 (304)
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights
American Journal of Hematology, EarlyView.CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin +3 more
wiley +1 more source
Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Immunohistochemical and molecular characterizations in urothelial carcinoma of bladder in patients less than 45 years [PDF]
, 2017 Dehner, Louis P, et al,
core +1 more source
The Anatomical Record, EarlyView.Abstract To solidify their power over society, totalitarian regimes will usually eliminate any dissent, any perceived threats early on. These threats include not only political enemies but also educated and independent segments of society, such as professional associations.
Michael Hortsch
wiley +1 more source
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American Journal of Roentgenology, 1993
contrast-enhanced CTscanshowed themasswaswithinthecollecting system (Fig.1B).Thebladder andure-terwerenormal, andresultsofcytologic examination oftheurinewerenormal. Afternephroureterectomy, abulky,ses-sile,papillary tumor arising fromtheuroepithelium wasfoundintheupperpole.Microscopy revealed focalinvasionoftherenalparenchyma, andthefinalpathologic ...
M H, Lev, F S, Chew
openaire +2 more sources
contrast-enhanced CTscanshowed themasswaswithinthecollecting system (Fig.1B).Thebladder andure-terwerenormal, andresultsofcytologic examination oftheurinewerenormal. Afternephroureterectomy, abulky,ses-sile,papillary tumor arising fromtheuroepithelium wasfoundintheupperpole.Microscopy revealed focalinvasionoftherenalparenchyma, andthefinalpathologic ...
M H, Lev, F S, Chew
openaire +2 more sources