Results 141 to 150 of about 10,131 (252)

GOA-1 regulates spermathecal transits. [PDF]

MicroPubl Biol
Sadeghian F, Sjoelund V, Cram EJ.
europepmc   +1 more source

Transitions [PDF]

Journal of PeriAnesthesia Nursing, 2005
openaire   +3 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Narwhal acoustic presence in Eclipse Sound, Nunavut: relationships with sea ice and responses to ships. [PDF]

Sci Rep
Ewing JP, Hidalgo-Pla E, Solsona-Berga A, Frasier KE, Ootoowak AJ, Westdal KH, Wiggins SM, Hildebrand JA, Jones JM.   +8 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Transits, journeys, bifurcations: in-bodied emotions

Revista Latinoamericana de Estudios sobre Cuerpos, Emociones y Sociedad, 2017
Adrián Scribano
doaj  

A chip-scale atomic beam for nonclassical light. [PDF]

Sci Adv
Larsen BJ, Hensley H, Martinez GD, Staron A, McGehee WR, Kitching J, Thompson JK.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Hyperactive deoxy-PIEZO1 shapes the circulatory life cycle of irreversibly sickled cells. [PDF]

Biophys J
Lew VL, Rogers SD.
europepmc   +1 more source

Transitions in Transitivity

Entangled Religions - Interdisciplinary Journal for the Study of Religious Contact and Transfer
The Seminal Heart (snying thig) is a form of the Tibetan Buddhist Great Perfection (rdzogs chen) tradition, which itself has been marked by a complex array of contemplative practices that have changed dramatically since its inception in the eighth century right up to present times.
openaire   +1 more source