Results 61 to 70 of about 9,880 (233)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Hundreds of TESS Exoplanets Might Be Larger than We Thought

open access: yesThe Astrophysical Journal Letters
The radius of a planet is a fundamental parameter that probes its composition and habitability. Precise radius measurements are typically derived from the fraction of starlight blocked when a planet transits its host star.
Te Han   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Differential Rotation of CoRoT Stars and a Kepler Binary Star from Starspot Transit Mapping

open access: yesThe Astrophysical Journal
While direct magnetic field measurements are rare for slowly rotating stars, spots observed during planetary transits provide a potential indicator of magnetic activity on stellar surfaces.
Adriana Valio   +2 more
doaj   +1 more source

All-inorganic cesium lead iodide perovskite solar cells with stabilized efficiency beyond 15%

open access: yesNature Communications, 2018
Black phase cesium lead iodide perovskite is regarded as a promising candidate for solar cells, but it easily transits to undesired yellow phase. Herein, Wang et al. stabilized the black phase using molecular additives to achieve device efficiency beyond
Kang Wang   +8 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Surviving in the Hot-Neptune Desert: The Discovery of the Ultrahot Neptune TOI-3261b

open access: yesThe Astronomical Journal
The recent discoveries of Neptune-sized ultra-short-period planets (USPs) challenge existing planet formation theories. It is unclear whether these residents of the Hot Neptune Desert have similar origins to smaller, rocky USPs, or if this discrete ...
Emma Nabbie   +47 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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