Results 61 to 70 of about 84,662 (294)

Surviving in the Hot-Neptune Desert: The Discovery of the Ultrahot Neptune TOI-3261b

open access: yesThe Astronomical Journal
The recent discoveries of Neptune-sized ultra-short-period planets (USPs) challenge existing planet formation theories. It is unclear whether these residents of the Hot Neptune Desert have similar origins to smaller, rocky USPs, or if this discrete ...
Emma Nabbie   +47 more
doaj   +1 more source

Transition

open access: yesDéveloppement durable et territoires, 2022
Fofack-Garcia, Rhoda, Maillefert, Muriel
openaire   +3 more sources

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

All-inorganic cesium lead iodide perovskite solar cells with stabilized efficiency beyond 15%

open access: yesNature Communications, 2018
Black phase cesium lead iodide perovskite is regarded as a promising candidate for solar cells, but it easily transits to undesired yellow phase. Herein, Wang et al. stabilized the black phase using molecular additives to achieve device efficiency beyond
Kang Wang   +8 more
doaj   +1 more source

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

open access: yesFEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu   +5 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Origins of Super Jupiters: TOI-2145b has a Moderately Eccentric and Nearly Aligned Orbit

open access: yesThe Astronomical Journal
Super Jupiters are giant planets with several Jupiter masses. It remains an open question whether these planets originate with such high masses or grow through collisions.
Jiayin Dong   +17 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

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