Results 21 to 30 of about 19,193 (244)

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

Hepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein   +21 more
wiley   +1 more source

A novel score predicts mortality after transjugular intrahepatic portosystemic shunt: MOTS ‐ Modified TIPS Score

Liver international (Print), 2022
The high risk for severe shunting‐related post‐interventional complications demands a stringent selection of candidates for transjugular intrahepatic portosystemic shunt (TIPS).
L. Fürschuß, F. Rainer, M. Effenberger, M. Niederreiter, R. Portugaller, A. Horvath, P. Fickert, V. Stadlbauer   +7 more
semanticscholar   +1 more source

Preliminary clinical observation of double C-arm digital subtraction angiography guidance during transjugular intrahepatic portosystemic shunt placement

BMC Gastroenterology, 2023
Background This study aimed to investigate the safety, preliminary clinical experience, and technical advantages of double C-arm digital subtraction angiography -assisted portal vein puncture for transjugular intrahepatic portosystemic shunt.
Jianqiao Chen, Xiao Bai, Chunyan Wang, Jihua Li, Weiguo Xu   +4 more
doaj   +1 more source

Combination of Model for End‐Stage Liver Disease and Lactate Predicts Death in Patients Treated With Salvage Transjugular Intrahepatic Portosystemic Shunt for Refractory Variceal Bleeding

Hepatology, 2021
Data about the prognosis of salvage transjugular intrahepatic portosystemic shunt (TIPS) using covered stents for refractory variceal bleeding caused by portal hypertension are scarce.
A. Walter, M. Rudler, P. Olivas, L. Moga, E. Trépo, M. Robic, I. Ollivier-Hourmand, A. Baiges, O. Sutter, C. Bouzbib, J. Péron, V. Le Pennec, N. Ganne-Carrié, J. García‐Pagán, M. Mallet, Hélène Larrue, T. Dao, D. Thabut, V. Hernández-Gea, J. Nault, C. Bureau, M. Allaire   +21 more
semanticscholar   +1 more source

A rare case of severe tricuspid regurgitation caused by detached stent falling into the right ventricle after transjugular intrahepatic portosystemic shunt

Journal of Cardiothoracic Surgery, 2022
Background Transjugular intrahepatic portosystemic shunt (TIPS) is an important method to alleviate cirrhotic portal hypertension. But the falling and fracture of the stent which detaches into the heart is a potentially fatal threat. Case presentation We
Feng Xiong, Kunyue Tan, Lijian Cheng, Yong Luo, Zhengkai Zhao   +4 more
doaj   +1 more source

Effect of time to pre‐emptive transjugular intrahepatic portosystemic shunt on patient outcome, a UK multicentre cohort study

Alimentary Pharmacology and Therapeutics, 2022
Pre‐emptive transjugular intrahepatic portosystemic shunt (pTIPSS) should be considered within 72 hours following acute oesophageal variceal bleeding.
P. Dunne, J. Finkel, F. Khan, N. Lachlan, D. Patch, D. Tripathi, A. Stanley, Peter C. Hayes   +7 more
semanticscholar   +1 more source

The role of transjugular intrahepatic portosystemic shunt in patients with portal hypertension: Advantages and pitfalls

Clinical and Molecular Hepatology, 2021
Transjugular intrahepatic portosystemic shunt (TIPS) is an effective interventional procedure to relieve portal hypertension, which is a main mechanism for the development of complications of liver cirrhosis (LC), such as variceal hemorrhage, ascites ...
H. Lee, S. Lee
semanticscholar   +1 more source

Transjugular Intrahepatic Portosystemic Shunt [PDF]

Seminars in Interventional Radiology, 2008
Transjugular intrahepatic portosystemic shunt (TIPS) insertion is among the most technically challenging procedures in interventional radiology. It combines many of the skills used in other procedures such as venous access, biopsy, angioplasty, and stent-graft insertion into one IR tour de force.
openaire   +3 more sources

Technical and Medium-Term Clinical Outcomes of Transjugular Intrahepatic Portosystemic Shunt with Fluoroscopy and Additional Trans-abdominal Ultrasound Guidance

Indian Journal of Radiology and Imaging, 2021
Background and Objective The aim of the study is to evaluate the technical and clinical outcomes of transjugular intrahepatic portosystemic shunt (TIPS) performed with additional transabdominal ultrasound guidance.
Shyamkumar N. Keshava, Vinu Moses, Anand Sharma, Munawwar Ahmed, Sathya Narayanan, Aswin Padmanabhan, Ashish Goel, Uday Zachariah, C.E. Eapen   +8 more
doaj   +1 more source

Transjugular intrahepatic portosystemic stent shunts. [PDF]

Gut, 1994
The transjugular intrahepatic portosystemic stent shunt (TIPSS) is essentially a side-to-side portocaval shunt performed by interventional radiological methods which connects the hepatic vein to the portal vein via the liver parenchyma. It can be performed successfully in 85% to 95% patients. The procedure mortality is low (1% to 2%) and is mainly from
P C, Hayes, D N, Redhead, N D, Finlayson
openaire   +3 more sources