Results 31 to 40 of about 318,913 (308)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Non-professional interpreters in counselling for asylum seeking and refugee women Filiz Celik, Tom Cheesman

Torture, 2018
Introduction: Non-professional interpreting warrants further study, particularly in environments where professional interpreters are scarce. Method: The lead researcher (a qualified interpreter and counsellor) joined 32 group sessions as a participant
Filiz Celik, Tom Cheesman
doaj   +1 more source

Psychometric properties of the Headache Under-Response to Treatment (HURT) questionnaire and the Migraine Disability Assessment Test (MIDAS) translated to Serbian [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. The Headache Under-Response to Treatment (HURT) questionnaire and the Migraine Disability Assessment Test (MIDAS), which are intended for assessing the headache-related disability, impact (MIDAS) and management (HURT), were not yet ...
Živković-Zarić Radica, Janković Slobodan M., Csépány Éva, Gyüre Tamás, Ertsey Csaba, Anđelković Marija   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Translating Cultures at Northumbria: @Trans_Cultures @NorthumbriaUni

, 2015
One of the most satisfying and enlightening elements of the leadership fellowship is the opportunity it affords to visit institutions, talk about the latest developments in ‘translating cultures’ – and, most importantly, to learn more about the projects ...
Charles Forsdick
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Translation to Serbian, cultural adaptation, reliability testing and validation of the questionnaire estimating the fear of injections [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. The two-part questionnaire called Injection Phobia Scale (IPS)-Anxiety and IPS-Avoidance represents one of the most commonly used questionnaires for assessing the fear of injections.
Aleksić Dejan Z., Milosavljević Miloš N., Bukonjić Andriana M., Milovanović Jasmina R., Protrka Zoran M., Radonjić Vesela B., Janković Slobodan M., Stefanović Srđan M.   +7 more
doaj   +1 more source

Why is translation relevant today: ideas for future translators

Language, Culture, Politics, 2023
Cultural, educational and professional frameworks recognised by our civilization have been formulated as texts. Translation is the only method allowing for their global dissemination. Religions, literatures, learning theories and organizational cultures
Konrad Klimkowski
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Beckett in Sweden Then and Now: (Re)Translating Waiting for Godot

, 2021
Palmstierna Einarsson compares two mainstay Swedish translations of Samuel Beckett’s Waiting for Godot, namely, Göran O. and Lill-Inger Eriksson’s translation from 1954, and Magnus Hedlund’s re-translation from 1990.
Charlotta Palmstierna Einarsson, Palmstierna Einarsson, Charlotta,   +1 more
core   +1 more source