Results 61 to 70 of about 394,172 (251)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Non-professional interpreters in counselling for asylum seeking and refugee women Filiz Celik, Tom Cheesman

Torture, 2018
Introduction: Non-professional interpreting warrants further study, particularly in environments where professional interpreters are scarce. Method: The lead researcher (a qualified interpreter and counsellor) joined 32 group sessions as a ...
Filiz Celik, Tom Cheesman
doaj   +1 more source

‘Translating China’: diasporic translations

, 2013
Last Friday's workshop of the AHRC ‘Translating Cultures’ network on ‘Translating China’ brought this stage of the project to a conclusion, completing a fascinating series of events on topics including archiving China in Britain (full details of all of ...
Charles Forsdick
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Adaptação transcultural para o Brasil do Dietary Sodium Restriction Questionnaire (Questionário Restritivo da Dieta de Sódio) (DSRQ) Adaptación transcultural para Brasil del dietary sodium restriction questionnaire (Cuestionario Restrictivo de la Dieta de Sodio) (DSRQ) Cross-cultural adaptation into Brazilian portuguese of the Dietary Sodium Restriction Questionnaire (DSRQ)

Arquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: A restrição de sódio é uma medida não farmacológica frequentemente orientada aos pacientes com Insuficiência Cardíaca (IC). No entanto, a adesão é de baixa prevalência, ficando entre as causas mais frequentes de descompensação da IC.
Karina Sanches Machado d'Almeida, Gabriela Correa Souza, Eneida Rejane Rabelo   +2 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Brazilian-Portuguese translation, cross-cultural adaptation and validation of the Myasthenia Gravis Composite scale. A multicentric study

Arquivos de Neuro-Psiquiatria
Objective To perform the translation, cultural adaptation and validation of the Myasthenia Gravis Composite (MGC) scale in Brazil. Methods The study was conducted at three neuromuscular disease research centers in accordance with the international ...
Ezequiel Fernandes Oliveira, Valéria Cavalcante Lima, Eduardo Araujo Perez, Melissa Nunes Polaro, Berenice Cataldo Oliveira Valério, João R Pereiro, Sergio Roberto Nacif, Claudia Santos Oliveira, Acary Souza Bulle Oliveira, Luis Vicente Franco Oliveira   +9 more
doaj   +1 more source

Translated Literature in Contemporary Slovenia

Knygotyra, 2020
Based on a typological model borrowed from sociology, this article analyzes literary translation support mechanisms in the world and especially in Slovenia.
Andrej Blatnik
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source