Results 71 to 80 of about 318,913 (308)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Translating Cultures: French Caribbean History, Literature and Migration

open access: yes, 2018
Translating Cultures: French Caribbean History, Literature and Migration Monday 24 September 2018, 10.15 -17:00, British Library Knowledge Centre A study day organised in partnership with the AHRC ‘Translating Cultures’ theme, the Eccles Centre for ...
Charles Forsdick
core  

To Translate or not to Translate? [PDF]

open access: yesMeta: Journal des traducteurs, 1985
A partir d'exemples sur les difficultes de la traduction tirees de la litterature et en particulier de la poesie («les correspondances» de Baudelaire), est recense l'ensemble des problemes, souvent incontournables que pose la langue a un traducteur charge de trouver d'une langue a une autre un concept ...
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Call for Papers: Translating the Literatures of Small European Nations

open access: yes, 2014
Call for Papers: Translating the Literatures of Small European Nations International Conference, University of Bristol, September 8th-10th 2015 Conference Organisers: Dr Rajendra Chitnis (Bristol), Dr Rhian Atkin (Cardiff), Professor Zoran Milutinovic ...
Charles Forsdick
core   +1 more source

From momentarity to perfective multiplicity. Different aspects of the aorist

open access: yesCognitive Studies | Études cognitives, 2015
From momentarity to perfective multiplicity. Different aspects of the aorist The aim of this work is a analysis of temporal meanings, and aspectual research.
Joanna Satoła-Staśkowiak
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

‘Translating Cultures’, in 100 Objects?

open access: yes, 2013
I was delighted last week to receive from Genevieve Warwick at the University of Edinburgh the latest issue of Art History, journal of the Association of Art Historians.
Charles Forsdick
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The challenge of translating Brian Friel's translations

open access: yes, 2001
Introduction: «Translations is a modern classic» (Daily Telegraph). «[...] The most deeply involved with Ireland but also the most universal: haunting and hard, lyrical and erudite, bitter and forgiving, both praise and lament» (Sunday Times).
Mazzara, F., Philippopoulou, D.
core  

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