Results 141 to 150 of about 1,773,214 (315)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Translating Creative Texts through Machine Translation: Deepl vs. Google Translate

Together with advancements in technology, there is an ongoing change in Translation Studies as more and more technological tools are being developed and implemented.
Sırkıntı, Hulisi Alp, Sırkıntı, Halise Gülmüş   +1 more
core   +1 more source

Decoy Nanoparticles and Protein Corona Modulation: A Novel Frontier in Sepsis Treatment

International Journal of Nanomedicine
Evgeniya R Denisova,1 Darya S Volkova,1 Valeria V Streltsova,1 Stepan A Kopytov,1 Artem S Krivosheev,1 Elizaveta V Panfilova,1 Neng Yan,2 Dmitry Kostyushev,3– 6 Mazdak Ganjalikhani-Hakemi,7 Vadim S Pokrovsky,8,9 Manu Lopus,10 Andrey V Golovin,1,6 Andrey ...
Denisova ER, Volkova DS, Streltsova VV, Kopytov SA, Krivosheev AS, Panfilova EV, Yan N, Kostyushev D, Ganjalikhani-Hakemi M, Pokrovsky VS, Lopus M, Golovin AV, Zamyatnin Jr AA, Celia C, Parodi A   +14 more
doaj  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study

NPP-Digital Psychiatry and Neuroscience
Personalized data-driven interventions for depression are much needed. Here, we leveraged N-of-1 machine learning (ML) to optimally target behavioral lifestyle interventions for depression.
Jason Nan, Suzanna Purpura, Satish Jaiswal, Houtan Afshar, Vojislav Maric, James K. Manchanda, Charles T. Taylor, Dhakshin Ramanathan, Jyoti Mishra   +8 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Literary translation and cultural memory [PDF]

, 2008
This article intends to investigate the relationship between literary translation and cultural memory, using a twentieth century film version of one of Shakespeare’s plays as a case study in inter-semiotic translation.
Long, Lynne
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Impact of translation workflows with and without MT on textual characteristics in literary translation [PDF]

Publisher Copyright: © 2024 The authors.The use of machine translation is increasingly being explored for the translation of literary texts, but there is still a lot of uncertainty about the optimal translation workflow in these scenarios.
MacKen, Lieve, Daems, Joke, Ruffo, Paola
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source