Results 171 to 180 of about 5,276,450 (332)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

The regulation, function and disease relevance of cytoplasmic tRNAs. [PDF]

Nat Rev Mol Cell Biol
Stanley RE, Lowe TM, Ignatova Z.
europepmc   +1 more source

Principles of Good Practice for the Translation and Cultural Adaptation Process for Patient-Reported Outcomes (PRO) Measures: report of the ISPOR Task Force for Translation and Cultural Adaptation.

Value in Health, 2005
D. Wild, A. Grove, Mona Martin, S. Eremenco, Sandra McElroy, A. Verjee-Lorenz, Pennifer Erikson   +6 more
semanticscholar   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Computational prediction-combined proteogenomics unveils widespread non-AUG translation initiation events in plants. [PDF]

Nucleic Acids Res
Zhang Y, Chang B, Wang S, Tian L, Zhao H, Luo W, Zhang H, Zhang S, Wu S, Wu L.   +9 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Contemporary Chinese newspaper discourse on translation: A mixed-methods approach to the People's Daily (1949-2023). [PDF]

PLoS One
Shi X, Huang L.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Improving survival in childhood acute lymphoblastic leukemia (ISCALL): An adaptive mixed-method hub-spoke model of implementation of the ICiCLe standard of care across India

Pediatric Hematology Oncology Journal
Shreya Ghosh, Sameer Bakhshi, Rachna Seth, Amita Trehan, Nirmalya Roy Moulik, Pritam Singha Roy, Smita Kayal, T. Priyakumari, Anand Prakash, Akash Kumar, Sumita Chaudhry, Narendra Kumar Chaudhary, Shilpa Khanna Arora, Nidhi Chopra, Piali Mandal, Siyaram Didel, Prashant Chhabra, Vyas Rathaur, Alka Yadav, Sanjeev Digra, Vishvdeep Khushoo, Raghwesh Ranjan, Velagala Swetha Venkatareddy, Aditi Lingayat, Sonali Mohapatra, Munlima Hazarika, Rachana Chennamaneni, Stuti Bhargava, Nandana Das, Venkatraman Radhakrishnan   +29 more
doaj   +1 more source

The Alteromonas macleodii ribosome enables consecutive incorporation of bulky D-amino acids into peptides. [PDF]

Nucleic Acids Res
Katoh T, Takada H, Sigal M, Suga H.
europepmc   +1 more source