Results 181 to 190 of about 5,276,450 (332)

10 Years of GWAS Discovery: Biology, Function, and Translation.

American Journal of Human Genetics, 2017
P. Visscher, N. Wray, Qian Zhang, P. Sklar, M. McCarthy, M. Brown, Jian Yang   +6 more
semanticscholar   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Translation and Cultural Adaption of the Revised ICU Family Satisfaction Questionnaire (FS-ICU-24R) Into Danish. [PDF]

Acta Anaesthesiol Scand
Ågård AS, Jepsen AT, Frydendal CK, Donovan K, Nielsen TH, Heyland DK, Nielsen AH.   +6 more
europepmc   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Translational control of Toxoplasma gondii differentiation. [PDF]

Biosci Rep
Wang F.
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Single-mRNA imaging and modeling reveal coupled translation initiation and elongation rates. [PDF]

Elife
Lamberti I, Chao JA, Gobet C, Naef F.
europepmc   +1 more source

Translation and normativity [PDF]

, 1999
Hermans, T
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Effectiveness of Dynamic Brace in Posterior Tibial Translation in Acute PCL Lesion: A Pilot, Single Center Exploratory Study. [PDF]

Healthcare (Basel)
Zappalà G, Delmedico M, Ciclamini D, Trapella N, Pasquali C, Crespi C, Ronga M.   +6 more
europepmc   +1 more source