Results 31 to 40 of about 1,357,475 (274)

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

FEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr, Klaus Mayer, Raffael Schaffrath, Johannes Buchner, Ulrich Brinkmann   +4 more
wiley   +1 more source

Addressing the quality of paediatric primary care: health worker and caregiver perspectives from a process evaluation of PACK child, a health systems intervention in South Africa

BMC Pediatrics, 2021
Background The WHO’s Integrated Management of Childhood Illness (IMCI) has resulted in progress in addressing infant and child mortality. However, unmet needs of children continue to present a burden upon primary healthcare services.
Robyn Curran, Jamie Murdoch, Max Bachmann, Eric Bateman, Ruth Cornick, Sandra Picken, Makhosazana Lungile Simelane, Lara Fairall   +7 more
doaj   +1 more source

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

FEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka, Takahiro Ogawa, Rikako Tsukida, Keiichi Noguchi, David Hibbett, Yoko Katayama, Makoto Yoshida   +6 more
wiley   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

Translation Studies and Corpus Linguistics: Introducing the Pannonia Corpus

Acta Universitatis Sapientiae: Philologica, 2017
The tools of corpus linguistics have become indispensable for research in descriptive translation studies (DTS), which aims to describe the characteristics of the translation process, and translational texts.
Robin Edina, Götz Andrea, Pataky Éva, Szegh Henriette   +3 more
doaj   +1 more source

Fabrication and characterization of mechanically competent 3D printed polycaprolactone-reduced graphene oxide scaffolds

Scientific Reports, 2020
The ability to produce constructs with a high control over the bulk geometry and internal architecture has situated 3D printing as an attractive fabrication technique for scaffolds.
Amir Seyedsalehi, Leila Daneshmandi, Mohammed Barajaa, John Riordan, Cato T. Laurencin   +4 more
doaj   +1 more source

Technical Infrastructures of Historical Translation Knowledge: A Call for the use of the Digital Library and Bibliography of Literature in Translation

Chronotopos, 2022
Editorial in English and German on the technical infrastructures relevant for translation history. The editors share an invitation to make use of the Digital Library and Bibliography of Literature in Translation (DLBT) and discuss the needs of ...
Larisa Schippel, Julia Richter, Tomasz Rozmyslowicz , Stefanie Kremmel   +3 more
doaj   +1 more source

Translation of Moufang's "Grundlagen der Geometrie" [PDF]

arXiv, 2020
This is an English translation of Moufang's notes "Grundlagen der Geometrie" at the University of Frankfurt in 1948, with added notes by the translator.
arxiv  

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Projection of the future diabetes burden in the United States through 2060

Population Health Metrics, 2018
Background In the United States, diabetes has increased rapidly, exceeding prior predictions. Projections of the future diabetes burden need to reflect changes in incidence, mortality, and demographics.
Ji Lin, Theodore J. Thompson, Yiling J. Cheng, Xiaohui Zhuo, Ping Zhang, Edward Gregg, Deborah B. Rolka   +6 more
doaj   +1 more source