Results 61 to 70 of about 5,227,080 (312)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Molecular Engineering of Polymyxin B for Imaging and Treatment of Bacterial Infections

Frontiers in Chemistry, 2022
The emergence of multi-drug resistant bacteria and the lack of novel antibiotics to combat them have led to the revival of polymyxin B, a previously abandoned antibiotic due to its potential nephrotoxicity and neurotoxicity.
Minghao Wu, Shipeng He, Hua Tang, Honggang Hu, Yejiao Shi, Yejiao Shi   +5 more
doaj   +1 more source

Google’s Multilingual Neural Machine Translation System: Enabling Zero-Shot Translation [PDF]

Transactions of the Association for Computational Linguistics, 2016
We propose a simple solution to use a single Neural Machine Translation (NMT) model to translate between multiple languages. Our solution requires no changes to the model architecture from a standard NMT system but instead introduces an artificial token ...
Melvin Johnson, M. Schuster, Quoc V. Le, M. Krikun, Yonghui Wu, Z. Chen, Nikhil Thorat, F. Viégas, M. Wattenberg, Gregory S. Corrado, Macduff Hughes, Jeffrey Dean   +11 more
semanticscholar   +1 more source

How Should Translation Competence Be Taught: a Quest for a Better Approach in Translation Class [PDF]

, 2015
It is widely agreed that the main aim of translation education is to develop students' translation competence, therefore most researches in translation education contexts focus on identifying the components of transla-tion competence and appropriate ...
Alim, C. N. (Condro)
core  

Translation elongation can control translation initiation on eukaryotic mRNAs [PDF]

, 2013
Synonymous codons encode the same amino acid, but differ in other biophysical properties. The evolutionary selection of codons whose properties are optimal for a cell generates the phenomenon of codon bias.
Aitken, Anand, Brachmann, Browne, Carlini, Chan, Charneski, Chu, Chu, Chu, Ciandrini, Dana, Firczuk, Fluitt, Gibson, Gould, Grant, Haar, Haar, Hense, Hershberg, Hu, Ikemura, Ingolia, Ingolia, Jeon, Kemp, Kotula, Kudla, Liti, Liu, Lombardi, McCarthy, Merritt, Mirzaei, Moriya, Mossadegh, Nagata, Neafsey, Outchkourov, Patel, Plant, Powell, Qian, Sala-Newby, Salas-Marco, Shalgi, Sikorski, Sinclair, Slimko, Stadler, Stark, Wolin, Yadava, Zhou, Zouridis   +55 more
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

TermEval: an automatic metric for evaluating terminology translation in MT [PDF]

, 2019
Terminology translation plays a crucial role in domain-specific machine translation (MT). Preservation of domain-knowledge from source to target is arguably the most concerning factor for the customers in translation industry, especially for critical ...
Haque, Rejwanul, Hasanuzzaman, Mohammed, Way, Andy   +2 more
core  

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The ethics of machine translation [PDF]

, 2011
In this paper I first describe the two main branches in machine translation research. I then go to discuss why the second of these, statistical machine translation, can cause some malaise among translation scholars.
Kenny, Dorothy
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source