Results 91 to 100 of about 15,259 (196)

Cryo-EM structure of ribosome from pathogenic protozoa Entamoeba histolytica reveals unique features of its architecture

Nature Communications
Entamoeba histolytica, an anaerobic protozoan parasite, is the causative agent of amoebiasis, bloody diarrhea, and liver abscesses in humans. Amoebiasis is more predominant in tropical areas with poor sanitation conditions, and it remains the fourth ...
Shivani Sharma, Shalini Mishra, Samudrala Gourinath, Prem S. Kaushal   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Aptamers, Riboswitches, and Ribozymes in S. cerevisiae Synthetic Biology

, 2021
Among noncoding RNA sequences, riboswitches and ribozymes have attracted the attention of the synthetic biology community as circuit components for translation regulation.
Huanhuan Ge, Mario Andrea Marchisio
core   +1 more source

Translation Techniques of the Complex Sentences in Bilingual Textbook Biology 1 For Senior High School Year X Published by Yudhistira

ELT Forum: Journal of English Language Teaching, 2013
This final project was a study which analyzed the use of translation techniques in the bilingual textbook BIOLOGY 1for Senior High School Year X Published by Yudhistira. The study was done qualitatively.
Ikma Qurrota A'yun
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Beyond multi-class – structured learning for machine translation

, 2010
In this thesis, we explore and present machine learning (ML) approaches to a particularly challenging research area – machine translation (MT). The study aims at replacing or developing each component in the MT system with an appropriate discriminative ...
Ni, Y, Ni, Yizhao
core  

Cell-free microcompartmentalised transcription-translation for the prototyping of synthetic communication networks [PDF]

, 2019
Recent efforts in synthetic biology have shown the possibility of engineering distributed functions in populations of living cells, which requires the development of highly orthogonal, genetically encoded communication pathways.
van der Linden, Ardjan J., Greef, T.F.A. de, Huck, W.T.S., van Hest, Jan C.M., Greef, TFA Tom de, Pieters, PA Pascal, Hest, J.C.M. van, Huck, Wilhelm T S, Pieters, Pascal, Dubuc, E, Linden, A.J.B.M. van der, Linden, AJ Ardjan van der, Dubuc, E., Pieters, Pascal A., Huck, Wilhelm T.S., Hest, JCM Jan van, de Greef, Tom F.A., Dubuc, Emilien   +17 more
core   +1 more source

Integrated Regulation of HuR by Translation Repression and Protein Degradation Determines Pulsatile Expression of p53 Under DNA Damage

iScience, 2019
Summary: Expression of tumor suppressor p53 is regulated at multiple levels, disruption of which often leads to cancer. We have adopted an approach combining computational systems modeling with experimental validation to elucidate the translation ...
Abhishek Guha, Deepika Ahuja, Sukhen Das Mandal, Bibudha Parasar, Krishanu Deyasi, Debadrita Roy, Vasundhara Sharma, Belinda Willard, Anandamohan Ghosh, Partho Sarothi Ray   +9 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

On microRNA and the Need for Exploratory Experimentation in Post-Genomic Molecular Biology [PDF]

, 2007
This paper is devoted to an examination of the discovery, characterization, and analysis of the functions of microRNAs, which also serves as a vehicle for demonstrating the importance of exploratory experimentation in current (post-genomic) molecular ...
Burian, Richard M., Richard M. Burian
core