Results 211 to 220 of about 2,947,154 (398)
Molecular Oncology, EarlyView.We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Review article: shared disease mechanisms between non‐alcoholic fatty liver disease and metabolic syndrome – translating knowledge from systems biology to the bedside [PDF]
, 2019 Silvia Sookoian, Carlos J. Pirola
openalex +1 more source
Translating the biology of β common receptor-engaging cytokines into clinical medicine
, 2022 Harshita Pant +7 more
openalex +2 more sources
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Relevance of Translation Initiation in Diffuse Glioma Biology and its Therapeutic Potential [PDF]
, 2019 Marina Digregorio +5 more
openalex +1 more source
FEBS Open Bio, EarlyView.Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash +6 more
wiley +1 more source
Research Advances in Mast Cell Biology and Their Translation Into Novel Therapies for Anaphylaxis
, 2023 Melanie C. Dispenza +2 more
openalex +2 more sources