Results 61 to 70 of about 2,436,936 (150)

Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge

Bioinform., 2014
Motivation: Inferring how humans respond to external cues such as drugs, chemicals, viruses or hormones is an essential question in biomedicine. Very often, however, this question cannot be addressed because it is not possible to perform experiments in ...
Kahn Rhrissorrakrai, V. Belcastro, E. Bilal, R. Norel, C. Poussin, C. Mathis, Rémi H. J. Dulize, N. Ivanov, L. Alexopoulos, J. Rice, M. Peitsch, G. Stolovitzky, Pablo Meyer, J. Hoeng   +13 more
semanticscholar   +1 more source

Translation Techniques of the Complex Sentences in Bilingual Textbook Biology 1 For Senior High School Year X Published by Yudhistira

ELT Forum: Journal of English Language Teaching, 2013
This final project was a study which analyzed the use of translation techniques in the bilingual textbook BIOLOGY 1for Senior High School Year X Published by Yudhistira. The study was done qualitatively.
Ikma Qurrota A'yun
doaj   +1 more source

IRES-mediated cap-independent translation, a path leading to hidden proteome

Journal of Molecular Cell Biology, 2019
Most eukaryotic mRNAs are translated in a cap-dependent fashion; however, under stress conditions, the cap-independent translation driven by internal ribosomal entry sites (IRESs) can serve as an alternative mechanism for protein production.
Yun Yang, Zefeng Wang
semanticscholar   +1 more source

Clinical Translation of Nanomedicine.

Chemical Reviews, 2015
1. Introduction Nanomedicine, the application of nanotechnology to health and medicine, is a relatively new area of interdisciplinary science. The field involves a wide range of scientific disciplines, including physics, chemistry, engineering, biology,
Yuanzeng Min, J. Caster, M. Eblan, Andrew Z. Wang   +3 more
semanticscholar   +1 more source

Translation in Prokaryotes.

Cold Spring Harbor Perspectives in Biology, 2018
This review summarizes our current understanding of translation in prokaryotes, focusing on the mechanistic and structural aspects of each phase of translation: initiation, elongation, termination, and ribosome recycling.
M. Rodnina
semanticscholar   +1 more source

METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis

Nature Cell Biology, 2022
R. Su, Lei Dong, Yangchan Li, Min Gao, P. He, Wei Liu, Jiangbo Wei, Zhicong Zhao, Lei Gao, Li Han, Xiaolan Deng, Chenying Li, Emily A. Prince, B. Tan, Y. Qing, Xi Qin, Chao Shen, Meilin Xue, Keren Zhou, Zhenhua Chen, Jingling Xue, Wei Li, H. Qin, Xiwei Wu, Miao Sun, Y. Nam, C. Chen, Wendong Huang, D. Horne, Steven T Rosen, C. He, Jianjun Chen   +31 more
semanticscholar   +1 more source

Ribosome Profiling: Global Views of Translation.

Cold Spring Harbor Perspectives in Biology, 2018
The translation of messenger RNA (mRNA) into protein and the folding of the resulting protein into an active form are prerequisites for virtually every cellular process and represent the single largest investment of energy by cells.
Nicholas T. Ingolia, Jeffrey A. Hussmann, J. Weissman   +2 more
semanticscholar   +1 more source

A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X

Molecular Systems Biology
The road from transcription to protein synthesis is paved with many obstacles, allowing for several modes of post-transcriptional regulation of gene expression.
Ziad Jowhar, Albert Xu, Srivats Venkataramanan, Francesco Dossena, Mariah L Hoye, Debra L Silver, Stephen N Floor, Lorenzo Calviello   +7 more
doaj   +1 more source

Functional Translational Readthrough: A Systems Biology Perspective.

PLoS Genetics, 2016
Translational readthrough (TR) has come into renewed focus because systems biology approaches have identified the first human genes undergoing functional translational readthrough (FTR).
Fabian Schueren, Sven Thoms
doaj   +1 more source

Caloric Restriction Induces MicroRNAs to Improve Mitochondrial Proteostasis

iScience, 2019
Summary: Both caloric restriction (CR) and mitochondrial proteostasis are linked to longevity, but how CR maintains mitochondrial proteostasis in mammals remains elusive. MicroRNAs (miRNAs) are well known for gene silencing in cytoplasm and have recently
Ran Zhang, Xu Wang, Jia-Hua Qu, Bing Liu, Peng Zhang, Tao Zhang, Peng-Cheng Fan, Xiao-Man Wang, Guang-Yuan Xiao, Ye Su, Yan Xie, Yue Liu, Jian-Fei Pei, Zhu-Qin Zhang, De-Long Hao, Ping Xu, Hou-Zao Chen, De-Pei Liu   +17 more
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