Results 71 to 80 of about 2,991,765 (400)
Positional proteomics reveals differences in N-terminal proteoform stability [PDF]
, 2016 To understand the impact of alternative translation initiation on a proteome, we performed a proteome-wide study on protein turnover using positional proteomics and ribosome profiling to distinguish between N-terminal proteoforms of individual genes.
Brown JL +4 more
core +2 more sources
On the Ribosomal Density that Maximizes Protein Translation Rate. [PDF]
PLoS ONE, 2016 During mRNA translation, several ribosomes attach to the same mRNA molecule simultaneously translating it into a protein. This pipelining increases the protein translation rate.
Yoram Zarai +2 more
doaj +1 more source
Adaptive laboratory evolution of a genome-reduced Escherichia coli. [PDF]
, 2019 Synthetic biology aims to design and construct bacterial genomes harboring the minimum number of genes required for self-replicable life. However, the genome-reduced bacteria often show impaired growth under laboratory conditions that cannot be ...
Cho, Byung-Kwan +8 more
core +2 more sources
Exosome Theranostics: Biology and Translational Medicine
Theranostics, 2018 Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules, such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through exocytosis, are ingested by target cells, and can transfer biological signals between local or distant cells.
Chuanjiang He +4 more
openaire +3 more sources
Geographic variation in walking activity in the red flour beetle Tribolium castaneum
Population Ecology, EarlyView.This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley +1 more source
Caloric Restriction Induces MicroRNAs to Improve Mitochondrial Proteostasis
iScience, 2019 Summary: Both caloric restriction (CR) and mitochondrial proteostasis are linked to longevity, but how CR maintains mitochondrial proteostasis in mammals remains elusive. MicroRNAs (miRNAs) are well known for gene silencing in cytoplasm and have recently
Ran Zhang +17 more
doaj +1 more source
Quantitative principles of cis-translational control by general mRNA sequence features in eukaryotes. [PDF]
, 2019 BackgroundGeneral translational cis-elements are present in the mRNAs of all genes and affect the recruitment, assembly, and progress of preinitiation complexes and the ribosome under many physiological states.
A Battle +71 more
core +3 more sources
Population Ecology, EarlyView.Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi +3 more
wiley +1 more source
Synthetic biology in the UK – An outline of plans and progress
Synthetic and Systems Biotechnology, 2016 Synthetic biology is capable of delivering new solutions to key challenges spanning the bioeconomy, both nationally and internationally. Recognising this significant potential and the associated need to facilitate its translation and commercialisation ...
L.J. Clarke, R.I. Kitney
doaj +1 more source
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]
, 2009 The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core +1 more source