Results 71 to 80 of about 2,935,766 (379)

A VLP-Based Vaccine Displaying HBHA and MTP Antigens of Mycobacterium tuberculosis Induces Potentially Protective Immune Responses in M. tuberculosis H37Ra Infected Mice

open access: yesVaccines, 2023
Heparin-binding hemagglutinin (HBHA) and M. tuberculosis pili (MTP) are important antigens on the surface of Mycobacterium tuberculosis. To display these antigens effectively, the fusion protein HBHA-MTP with a molecular weight of 20 kD (L20) was ...
Juan Wang   +11 more
doaj   +1 more source

A remark on the frequent hypercyclicity criterion for weighted composition semigroups and an application to the linear von Foerster-Lasota equation

open access: yes, 2014
We generalize a result for the translation $C_0$-semigroup on $L^p(\R_+,\mu)$ about the equivalence of being chaotic and satisfying the Frequent Hypercyclicity criterion due to Mangino and Peris to certain weighted composition $C_0$-semigroups. Such $C_0$
Kalmes, Thomas
core   +1 more source

Positional proteomics reveals differences in N-terminal proteoform stability [PDF]

open access: yes, 2016
To understand the impact of alternative translation initiation on a proteome, we performed a proteome-wide study on protein turnover using positional proteomics and ribosome profiling to distinguish between N-terminal proteoforms of individual genes.
Brown JL   +4 more
core   +2 more sources

Caloric Restriction Induces MicroRNAs to Improve Mitochondrial Proteostasis

open access: yesiScience, 2019
Summary: Both caloric restriction (CR) and mitochondrial proteostasis are linked to longevity, but how CR maintains mitochondrial proteostasis in mammals remains elusive. MicroRNAs (miRNAs) are well known for gene silencing in cytoplasm and have recently
Ran Zhang   +17 more
doaj   +1 more source

On the Ribosomal Density that Maximizes Protein Translation Rate. [PDF]

open access: yesPLoS ONE, 2016
During mRNA translation, several ribosomes attach to the same mRNA molecule simultaneously translating it into a protein. This pipelining increases the protein translation rate.
Yoram Zarai   +2 more
doaj   +1 more source

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

open access: yesPopulation Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source

Exosome Theranostics: Biology and Translational Medicine

open access: yesTheranostics, 2018
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules, such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through exocytosis, are ingested by target cells, and can transfer biological signals between local or distant cells.
Chuanjiang He   +4 more
openaire   +3 more sources

Synthetic biology in the UK – An outline of plans and progress

open access: yesSynthetic and Systems Biotechnology, 2016
Synthetic biology is capable of delivering new solutions to key challenges spanning the bioeconomy, both nationally and internationally. Recognising this significant potential and the associated need to facilitate its translation and commercialisation ...
L.J. Clarke, R.I. Kitney
doaj   +1 more source

Interaction of yeast eIF4G with spliceosome components Implications in pre-mRNA processing events [PDF]

open access: yes, 2009
International audienceAs evidenced from mammalian cells the eukaryotic translation initiation factor eIF4G has a putative role in nuclear RNA metabolism. Here we investigate whether this role is conserved in the yeast Saccharomyces cerevisiae.
Barrass, J. David   +6 more
core   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

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