Results 131 to 140 of about 351,602 (281)

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

open access: yesAdvanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin   +14 more
wiley   +1 more source

A diagnostic assessment of translation competence: linguistic and intercultural gaps in Egyptian EFL programs

open access: yesLanguage Testing in Asia
This study offers a diagnostic assessment of the multifaceted challenges encountered by English as a Foreign Language (EFL) students enrolled in translation-focused programs at a large public Egyptian university.
Mohamed Mekheimer
doaj   +1 more source

DESIGNING SPEAKING TEST BETWEEN RESPONSIVE TEST AND IMITATIVE TEST FOR DEVELOPING VOCABULARY COMPETENCE [PDF]

open access: yes, 2012
Speaking and vocabulary are basic concept in teaching learning process, a teacher should be know how to construct and designing of speaking test related to vocabulary.
Nugroho , Setiawan Bayu
core  

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Il contributo della prospettiva sociologica sulla traduzione alla formazione e all'ethos professionale del traduttore specializzato [PDF]

open access: yes, 2006
pp.1-13Research on translation in general, and on specialised translation in particular, has long abandoned a purely linguistic perspective and has embraced principles and methodologies coming from neighbouring disciplines such as terminology ...
Palumbo, Giuseppe
core   +1 more source

Heuristically Adaptive Diffusion‐Model Evolutionary Strategy

open access: yesAdvanced Science, EarlyView.
Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl   +3 more
wiley   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

open access: yesAdvanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong   +13 more
wiley   +1 more source

The Effect of Pragmatic Competence on Saudi Translators’ Performance

open access: yesمجلة الدراسات الاجتماعية
This study aims to investigate the effect of pragmatic competence on the performance of Saudi translators. The researchers used a quantitative method to conduct this study.
Meshari Ali Alsairi   +1 more
doaj   +1 more source

Import of honeybee prepromelittin into the endoplasmic reticulum [PDF]

open access: yes, 1987
Honeybee prepromelittin is correctly processed and imported by dog pancreas microsomes. Insertion of prepromelittin into microsomal membranes, as assayed by signal sequence removal, does not depend on signal recognition particle (SRP) and docking protein.
Müller, Günter, Zimmermann, Richard
core   +2 more sources

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

open access: yesAdvanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong   +13 more
wiley   +1 more source

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