Results 211 to 220 of about 351,602 (281)

Spermatogenesis Beyond DNA: Integrated RNA Control of the Epitranscriptome and Three-Dimensional Genome Architecture. [PDF]

Curr Issues Mol Biol
Kaltsas A, Kyrgiafini MA, Mamuris Z, Chrisofos M, Sofikitis N.   +4 more
europepmc   +1 more source

Alternative Translation Initiation in PRKN Delays the Onset of Parkinson's Disease and Offers a Therapeutic Target

Annals of Neurology, EarlyView.
Objective Biallelic variants in PRKN cause autosomal recessive Parkinson's disease (PD) with a median age at onset of 31 years. When evaluating the 16 previously published carriers of a homozygous deletion of Exon 2 from the International Parkinson's Disease and Movement Disorder Society Gene Database (MDSGene) database, the median age at onset is ...
Arian Hach, Katja Lohmann, Manabu Funayama, Poornima J. Menon, Eva‐Juliane Vollstedt, Teresa Kleinz, Hiroyo Yoshino, Suzanne Lesage, Britta Meier, Carolyn M. Sue, Jean‐Christophe Corvol, Alexis Brice, Nobutaka Hattori, Christine Klein, Aleksandar Rakovic   +14 more
wiley   +1 more source

Regiodivergent C3 and C4 Amination of Quinolines via Radical and Ionic Pathways

Angewandte Chemie, EarlyView.
A regiodivergent strategy converts a single N‐aminoquinolinium precursor into either C3‐ or C4‐aminated quinolines. Nucleophile‐induced dearomatization diverges into light‐driven N‐centered radical capture (C3) or base‐promoted SNAr (C4), enabling rapid assembly of aminoquinoline libraries and late‐stage diversification.
Ye‐Eun Kim, Jieun Kim, Juyeon Lee, Sungwoo Hong   +3 more
wiley   +2 more sources

Self-Perceived Spiritual Care Competencies Among Nursing and Midwifery Students in Slovenia: A Cross-Sectional Study. [PDF]

Nurs Open
Mlinar Reljić N, Mcsherry W, Skubic M, Mihelič-Zajec A, Babnik K, Štrancar K, Karnjuš I.   +6 more
europepmc   +1 more source

Acoustofluidic Patterning for Improved Microtissue Histology

Advanced NanoBiomed Research, EarlyView.
Microtissue histology is widely used to characterize microtissue phenotype and morphology. However, conventional microtissue histology workflows are inefficient and time‐consuming. This work introduces a novel embedding technique that uses acoustofluidics to improve the efficiency of microtissue histology and reduce the time required for data analysis.
Dhananjay V. Deshmukh, Emilie Vuille‐dit‐Bille, Saumitra Joshi, Nicola Gerber, Christine Fux, Annina Eichenberger, Epifania Bono, Markus Rimann, Sarah Heub, Daniel Migliozzi, Stephanie Boder‐Pasche, Gilles Weder, Jurg Dual, Mark W. Tibbitt   +13 more
wiley   +1 more source

Direct Selection of Functional De Novo Macrocycles for Activation of On‐Cellulo Insulin Receptor

Angewandte Chemie, EarlyView.
A live‐cell screening platform, RaPID‐ExCells, integrates mRNA display‐derived macrocyclic peptide libraries with functional selection against native cell‐surface receptors. Application to the insulin receptor enabled de novo discovery of a macrocyclic agonist that activates endogenous signaling despite weak in vitro binding, highlighting the power of ...
Yun‐Hsuan Kuo, Emiko Mihara, Junichi Takagi, Hiroaki Suga   +3 more
wiley   +2 more sources

Extracellular vesicles in monitoring and modulation of oocyte competence: focus on exosomes. [PDF]

J Ovarian Res
Ezzati M, Izadpanah M.
europepmc   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Reliability and validity of the Turkish version of the digital competence questionnaire for nurses. [PDF]

BMC Nurs
Bulut A, Kasap Rİ, Yılmaz N.
europepmc   +1 more source

Public versus private clinical radiography training in Lagos State, Nigeria: a comparative cross-sectional survey of associations with graduate self-perceived competence and practice readiness. [PDF]

BMJ Open
Udo EO, Emordi OR, Kalu EI, Enebeli UU, Uzochukwu B, Kalu FA, Igwe PC, Kalu JJ, Kalu BO, Cherima YJ, Nwokenna US, Hassan RK, Amadi AN.   +12 more
europepmc   +1 more source