Results 61 to 70 of about 1,034,937 (268)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Comparison of Translation Strategies in the Old and New Translations of The 100: A Ranking of the Most Influential People in History by Michael Hart

Journal of Language and Literature
Translations of the same text might be different from one version to another based on the translation strategies that are used by the translator. By examining the translation strategies in the old and the new translations of a book titled The 100: A ...
Ananda Nayla, Haru Deliana Dewi
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Danube Region Terminology and Its Translation

Journal of Danubian Studies and Research, 2013
The article highlights the problems connected with the identification, defining and translation of terms in such spheres of the Danube region businesses as: shipping, trade and financing.
Olena Chetverikova
doaj  

Analysis of Techniques and Quality of Translation of Surah Yasin into Rejang Language

JL3T (Journal of Linguistics, Literature and Language Teaching)
This study investigated the translation of Surah Yasin from Arabic into the Rejang language, focusing on translation techniques and quality. The objective was to evaluate how meaning was preserved and conveyed through this localized translation.
Sakut Anshori, Muhammad Taqiyuddin, Rizki Indra Guci, Diana Hardiyanti   +3 more
doaj   +1 more source

Statistical Methods in Translational Medicine

Journal of the Formosan Medical Association, 2008
This study focuses on strategies and statistical considerations for assessment of translation in language (e.g. translation of case report forms in multinational clinical trials), information (e.g. translation of basic discoveries to the clinic) and technology (e.g.
Shein-Chung Chow, Siu-Keung Tse, Min Lin
openaire   +3 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Methods of Translating Vulgarisms in Film Translation in the Context of Transformations of Language Communication

Półrocznik Językoznawczy Tertium, 2018
The article is an attempt at systematizing methods used in film translation of swearwords / (vulgarisms) from English into Polish. The methods presented in the study were arrived at through extensive research, which aimed at describing translation ...
Magdalena Hądzlik-Białek
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source