Results 51 to 60 of about 29,075 (258)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Meaning does not have to be rendered in words: Intersemiotic translation in digital religious infographics

Indonesian Journal of Applied Linguistics
Data visualization is becoming widespread nowadays as people grasp images faster than verbal information. Infographics delineate information visually to be easily intelligible to the audience. They are creative discursive spaces where complex information
Mai Mowafy
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Poly[[tri-μ-cyanido-cyanido(1,4,10,13-tetraoxa-7,16-diazacyclooctadecane)barium(II)platinum(II)] hemihydrate]

Acta Crystallographica Section E, 2009
The title compound, {[BaPt(CN)4(C12H26N2O4)]·0.5H2O}n, is a two-dimensional coordination polymer in which the sheets are oriented approximately parallel to the (overline{1}01) set of crystal planes.
Marilyn M. Olmstead, Christine M. Beavers, Latisha Paw U   +2 more
doaj   +1 more source

Comparison of Roll and Pitch Among Patients with Vertical and Horizontal Skeletal Patterns Using Cant-O-Meter: A New Gyroscopic Device for Measuring Occlusal Cant

Journal of Indian Orthodontic Society, 2022
In Orthodontics, initial classification of malocclusions was based on planar malocclusions in the anteroposterior, transverse and vertical planes that were based only on translation of the jaws in space.
Janani Ravi, Poornima Jnaneshwar, R. Krishnaraj, K. Ravi   +3 more
doaj   +1 more source

A translation plane of order 112

Journal of Combinatorial Theory, Series A, 1983
AbstractA translation plane of order 112 is constructed. Its translation complement is a solvable group of order 1200 and has 9 orbits on the line at infinity. These orbits have lengths 30, 20, 20, 12, 10, 10, 10, 5, 5, respectively.
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

2-{(E)-N-[2-(1H-Inden-3-yl)ethyl]iminomethyl}-1H-imidazole

Acta Crystallographica Section E, 2011
The asymmetric unit of the title compound, C15H15N3, contains two crystallographically independent molecules with very similar geometries. The imidazole and indenyl planes are approximately orthogonal, making dihedral angles of 88.21 (9) and 83.
Zhao Li, Chong Tian, Wanli Nie, Maxim V. Borzov   +3 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Stable elastic nail application with poller K-wire for Irreducible distal radius metaphyseal-diaphyseal Junction fractures in preadolescents: a new operative technique

BMC Musculoskeletal Disorders
Background Surgical treatment of irreducible distal radius diaphyseal- metaphyseal junction fractures involves difficulties as the fracture remains too proximal for K-wire fixation and too distal for the elastic stable intramedullary nail. Our study aims
Levent Horoz, Mehmet Fevzi Cakmak, Cihan Kircil   +2 more
doaj   +1 more source