Results 61 to 70 of about 29,075 (258)

Sagittal instability with inversion is important to evaluate after syndesmosis injury and repair: a cadaveric robotic study

Journal of Experimental Orthopaedics, 2020
Purpose Disruption of the syndesmosis, the anterior-inferior tibiofibular ligament (AITFL), the posterior-inferior tibiofibular ligament (PITFL), and the interosseous membrane (IOM), leads to residual symptoms after an ankle injury. The objective of this
Neel K. Patel, Conor I. Murphy, Thomas R. Pfeiffer, Jan-Hendrik Naendrup, Jason P. Zlotnicki, Richard E. Debski, MaCalus V. Hogan, Volker Musahl   +7 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

5-Benzylidene-3-phenyl-2-phenylimino-1,3-thiazolidin-4-one

Acta Crystallographica Section E, 2011
The title compound, C22H16N2OS, is a chalcone analog with a thiazolidinone core that was synthesized as a potential cytotoxic and anticancer agent. The structure is commensurately modulated by unit-cell doubling along the direction of the a axis of the ...
Matthias Zeller, Vijay Satam, Ravi Kumar Bandi, Ajaya Kumar Behera, Bijay Kumar Mishra, Hari Pati, Moses Lee   +6 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Transposed translation planes [PDF]

Proceedings of the American Mathematical Society, 1975
A detailed study of the transposed translation planes which are also given by dual spreads is made using the matrix representation of translation planes.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

STYLISTIC MEANS OF IMPLEMENTING THE IDEA OF THE WORLD’S IRIDESCENCE IN PH.K. DICK’S “UBIK” IN THE CONTEXT OF TRANSLATION TRANSFORMATIONS [PDF]

Alfred Nobel University Journal of Philology
The article deals with the formation means of the idea of the world’s iridescence or illusiveness, its stylistic and translation aspects within the textual framework of Ph.K. Dick’s novel “Ubik” and its translat- ed version in Ukrainian. The relevance
Svitlana F. Aleksenko, Larysa I. Taranenko   +1 more
doaj   +1 more source

Quasifields of symplectic translation planes

Journal of Combinatorial Theory, Series A, 2009
Let \(V\) be a vector space over the field \(F\) and let \(\Sigma\) be a spread on \(V\), i.e.\ a covering of \(V\) by a collection of mutually complementary subspaces. If every element of \(\Sigma\) is totally isotropic w.r.t a non-degenerate symplectic bilinear form \(S : V\times V \rightarrow F\), then \(\Sigma\) is called a symplectic spread ...
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Di-tert-butyldiisothiocyanatotin(IV)

IUCrData
The title compound, [Sn(C4H9)2(NCS)2], which crystallizes with one and a half molecules in the asymmetric unit, represents a new structure type for intermolecular sulfur...tin interactions, which is characterized by an antiparallel (A) arrangement of the
Anne Kamrowski, Hans Reuter
doaj   +1 more source