Results 81 to 90 of about 30,282 (293)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Translation Planes and Derivation Sets

, 1989
Assmus, Jr., E.F.; Key, J.D.. (1989). Translation Planes and Derivation Sets.
Assmus, Jr., E.F., Key, J.D.
core  

5-Benzylidene-3-phenyl-2-phenylimino-1,3-thiazolidin-4-one

Acta Crystallographica Section E, 2011
The title compound, C22H16N2OS, is a chalcone analog with a thiazolidinone core that was synthesized as a potential cytotoxic and anticancer agent. The structure is commensurately modulated by unit-cell doubling along the direction of the a axis of the ...
Matthias Zeller, Vijay Satam, Ravi Kumar Bandi, Ajaya Kumar Behera, Bijay Kumar Mishra, Hari Pati, Moses Lee   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

On a class of translation planes of square order

, 1987
A class of translation planes of order q2, where q = pr, p is a prime, p ⩾7, p ≠± 1 (mod 10) and r is an odd natural number is constructed and the translation complements of these planes are determined.
Vithal Rao, G, Narayana Rao, M.L, Satyanarayana, K   +2 more
core   +1 more source

Di-tert-butyldiisothiocyanatotin(IV)

IUCrData
The title compound, [Sn(C4H9)2(NCS)2], which crystallizes with one and a half molecules in the asymmetric unit, represents a new structure type for intermolecular sulfur...tin interactions, which is characterized by an antiparallel (A) arrangement of the
Anne Kamrowski, Hans Reuter
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Femoral Translation in Patients with Unicompartmental Osteoarthritis—A Cohort Study

Biomechanics
The use of three-dimensional (3D) gait analysis to image femorotibial translation can aid in the diagnosis of pathology and provide additional insight into the severity of KOA (knee osteoarthritis). Femorotibial translation is of particular importance in
Mathis Wegner, Simon Kuwert, Stefan Kratzenstein, Maciej J. K. Simon, Babak Moradi   +4 more
doaj   +1 more source

STYLISTIC MEANS OF IMPLEMENTING THE IDEA OF THE WORLD’S IRIDESCENCE IN PH.K. DICK’S “UBIK” IN THE CONTEXT OF TRANSLATION TRANSFORMATIONS [PDF]

Alfred Nobel University Journal of Philology
The article deals with the formation means of the idea of the world’s iridescence or illusiveness, its stylistic and translation aspects within the textual framework of Ph.K. Dick’s novel “Ubik” and its translat- ed version in Ukrainian. The relevance
Svitlana F. Aleksenko, Larysa I. Taranenko   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source