Results 131 to 140 of about 368,172 (300)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A descriptive qualitative examination of knowledge translation practice among health researchers in Manitoba, Canada. [PDF]

BMC Health Serv Res, 2017
Sibley KM, Roche PL, Bell CP, Temple B, Wittmeier KDM.   +4 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Trainees’ self-reported challenges in knowledge translation practice and research [PDF]

BMC Health Serv Res, 2014
Urquhart R, Cornelissen E, Lal S, Newman K, Van Eerd D, Powell B, Chan V.   +6 more
europepmc   +1 more source

Translation of addictions science into practice

, 2007
Recent advances in the understanding of the genetic, neurochemical, behavioral and cultural underpinnings of addiction have led to rapid advances in the understanding of addiction as a disease.
Kavanagh, David, Miller, Peter
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

A portfolio of literary translation practice and translation analysis [PDF]

The Covering Document below aims to provide an overview of the range and coherence of my publication portfolio submitted for examination under the Warwick PhD by Publications programme, founded in the inter-related disciplines of academic translation ...
Corness, Patrick John
core  

Next generation translation and localization: Users are taking charge [PDF]

, 2010
Nonprofit translation activity driven by users and volunteer translators now represent a market force that easily rivals the mainstream translation and localization industries. While they still try to understand the drivers behind this nonprofit movement
O'Brien, Sharon, O\u27Brien, Sharon, Schäler, Reinhard   +2 more
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

EMOTIONAL CONCEPTUAL PROXIMATES AS CONSTRUCTS FOR DIFFERENTIATING BETWEEN CLOSE EMOTION CONCEPTS: A CASE STUDY OF HAPPINESS AND JOY

Filolog
The article identifies the semantic and affective parameters that distinguish between the close emotion concepts (ECs) happiness and joy in the Anglo-Saxon culture.
Kostiantyn Mizin, Liudmyla Slavova
doaj   +1 more source