Results 121 to 130 of about 1,125,514 (315)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Introducing translation studies : theories and applications

open access: yes, 2009
Introducing Translation Studies is the definitive guide to the theories and concepts that make up the dynamic field of translation studies. Providing an accessible and fully up-to-date overview of key movements and theorists within an expanding area of ...
Munday, Jeremy   +2 more
core  

Is machine translation gisting translation?

open access: yes
This article explores the question of whether machine translation (MT) is translation by analyzing the processes involved in a translator-led ‘traditional’ process against those involved in receiver-led MT gisting. Backed by evidence from recent research
Nurminen, Mary
core   +1 more source

Remapping Translation Studies: Towards a Translation Studies Ontology1 [PDF]

open access: yesMeta, 2008
Building on a common view of translation as a human intentional activity, this article presents a translation studies thesaurus in which all concepts from the multitude of different translation studies areas listed in Baker (1998a), the “Bibliography of Translation Studies” (1998-), Williams and Chesterman (2002) and the “EST-Directory 2003” are ...
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Chinese Mental Health Scale Translation [PDF]

open access: yes
This open access book illustrates the key steps and procedures of developing mental health scales into linguistically and culturally appropriate translations.
Shan, Yi, Ji, Meng
core   +1 more source

Current status of science learning in Shanghai and a possible PBL mechanism

open access: yesDiscover Education
China’s 2022 curriculum standards issued by the Ministry of Education prioritize a “competency-oriented” education that highlights the role of science education in improving students’ scientific literacy and competency.
Haiqin Sun, Zhiyuan Gu
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Introduction : advancing translation studies through language industry studies

open access: yes, 2022
Video introduction to panelIn recent years, the language industry, defined here as comprising the key elements of globalization (G11n), internationalization (I18n), localization (L10n) and translation (T9n), together with interpreting, consulting ...
Angelone, Erik   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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