Results 71 to 80 of about 1,438,651 (288)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Bulk-edge correspondence of one-dimensional quantum walks
, 2016 We outline a theory of symmetry protected topological phases of one-dimensional quantum walks. We assume spectral gaps around the symmetry-distinguished points +1 and -1, in which only discrete eigenvalues are allowed. The phase classification by integer
Cedzich, C. +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Spanish Journalists at the Epicentre of Power: From the Media to Institutions
Journalism and MediaThis article examines the work of journalists employed in communication offices within key centres of power, specifically, prominent institutions. It explores their professional self-perception, the working conditions they face, and how occupying such ...
Joaquín Aguar Torres
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Methis: Studia Humaniora Estonica, 2020 Artikkel annab ülevaate, kuidas on tõlketeoorias käsitletud autoritõlget − kirjandusteose tõlget teise keelde, mille on teinud selle autor ise. Lähemalt vaadeldakse ühte leksikaal-semantilist aspekti Jaan Kaplinski luuletuse „Valgus ei saagi vanaks ...
Ekaterina Velmezova
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
LanguagesThis study examines non-standard comparative and superlative adjective forms in Ukrainian and English, emphasizing their evaluative meanings and grammatical deviations.
Oksana Kovtun
doaj +1 more source
How to spice up a breakfast cereal or The translation of culturally bound referential items in “The bluest eye” by Toni Morrison and “Vineland” by Thomas Pynchon [PDF]
, 2013 This article will attempt to suggest translation procedures necessary to translate culturally bound items in the referential level of a literary work illustrated with examples from two novels: “The Bluest Eye” by Toni Morrison and “Vineland” by Thomas ...
Barciński, Łukasz
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