Results 271 to 280 of about 41,105 (341)

Efficient DNA-based data storage using shortmer combinatorial encoding. [PDF]

Sci Rep
Preuss I, Rosenberg M, Yakhini Z, Anavy L.   +3 more
europepmc   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Religiousness Measured by the Four Basic Dimensions of Religiousness Scale (4-BDRS) among Polish Believers: Measurement Quality, Personality and Well-being Correlates. [PDF]

J Relig Health
Szydłowski P, Topolewska-Siedzik E, Cieciuch J.   +2 more
europepmc   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Extended Grammar of Systematized Nomenclature of Medicine - Clinical Terms for Semantic Representation of Clinical Data: Methodological Study. [PDF]

J Med Internet Res
Gaudet-Blavignac C, Ehrsam J, Baumann M, Bensahla A, Mattei M, Zheng Y, Lovis C.   +6 more
europepmc   +1 more source

Semantic stability in translation : a behavioral-profile analysis of the semantic field of inchoativity in original Dutch and Dutch translated from English and French [PDF]

, 2019
De Baets, Pauline
core  

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Addressing Conceptual Gaps in Physician Leadership Development: A Critical Perspective. [PDF]

J Healthc Leadersh
Saxena A.
europepmc   +1 more source

EXPLICITATION AS A UNIVERSAL OF TRANSLATION AND COHESION AND COHERENCE IN TRANSLATION STUDIES

Kalinichenko T.M.
openalex   +1 more source