Results 91 to 100 of about 54,971,060 (296)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Personal Accountability of Medical Students in Medical Education [PDF]
, 2019 Producing graduates with sufficient practical competency is the main mission of every educational institution. Following the accreditation of the Korean Institute of Medical Education and Evaluation, medical schools have been stepping up efforts to ...
Korean Medical Education Review (의학교육논단)
core +1 more source
Social Marketing in Health-related Settings with an Emphasis on the Role of Knowledge Brokers
Rāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat, 2018 The role of the knowledge brokers as a human component has shown that by increasing human communication, there is a probability of changing behavior in the knowledge interpreters.
Farzaneh Sardari +1 more
doaj
Animal modeling in bone research—Should we follow the White Rabbit?
Animal Models and Experimental Medicine, 2019 Animal models are live subjects applied to translational research. They provide insights into human diseases and enhance biomedical knowledge. Livestock production has favored the pace of human social development over millennia.
Aline Schafrum Macedo +9 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
, 2006 Official program and abstracts from the twelfth annual Frank Tyler Fall Medical Student Research Symposium at the University of Utah.
Medical Student Research Program
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Medical Research Council of Ireland [PDF]
, 1981 The Council's commitment, as outlined in the rest of the report, has been in three main areas. Individual research projects are put forward by medical and scientific applicants in the universities and hospitals and are evaluated by expert sub ...
Medical Research Council of Ireland
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BMC Public Health, 2017 Background With increasing financial pressures on public health in England, the need for evidence of high relevance to policy is now stronger than ever.
Peter van der Graaf +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Medical Research Charities Group Annual Report 2017
, 2018 While we see first-hand the enormous impact our member organisations make on society every day, the value of our sector’s role is not always recognised at a national level or through their inclusion in discussions on health research policy and planning ...
Medical Research Charities Group
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