Deep forecasting of translational impact in medical research [PDF]
, 2021 Amy Nelson +12 more
openalex +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Medical Research Council of Ireland annual report for the year ended 31st December 1986
, 1986 By January, 1986 one year had passed since the meeting between the Minister for Health. Mr. Barry Desmond, and the Council in the Custom House. In the year under review matters moved more or less inexorably towards a merger of the functions of the ...
Medical Research Council of Ireland
core
Translational medical research in Nigeria: challenges, prospects and recommendations for the future [PDF]
, 2021 Afeez Abolarinwa Salami +1 more
openalex +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Medical Research Council of Ireland annual report for the year ended 31st March 1985
, 1985 The year under review started with the Council being invited to meet the Minister for Health, Mr. Barry Desmond, in early January. He proposed the merger of the Medico Social Research Board and the Medical Research Council with some elements of the ...
Medical Research Council of Ireland
core
32097 Title V Medical Sciences Campus Project (TVMSC) : Clinical and Translational Research (CTR) with an Interdisciplinary/Entrepreneurship (IE) approach for Students and Faculty (UgS, UgF) from Undergraduate Programs (UgP) in Puerto Rico: an initiative for an early jumpstart in CTR and Scientific Entrepreneurship (SE) in a virtual scenario 2020-25. [PDF]
, 2021 Margarita Irizarry Ramírez +6 more
openalex +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source