Utilising Large Language Models for the Automated Mapping of Medical Research to Translational Stages [PDF]
Matthew Clapham +3 more
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496 Transforming the pipeline towards independence in Clinical and Translational Research (CTR) through opportunities in research environments for underrepresented health professions faculty and students: The Title V Cooperative Project between University Puerto Rico Medical Sciences Campus and Universidad Central del Caribe (Title V Coop) [PDF]
, 2022 Margarita Irizarry Ramírez +3 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Translational medical research and liver transplantation: systematic review. [PDF]
Transl Gastroenterol Hepatol, 2018 Nacif LS +6 more
europepmc +1 more source
500 Building research knowledge base through training and elective courses in Clinical and Translational Research (CTR) as part of the Title V Cooperative Project (Title V Coop) between the University of Puerto Rico Medical Sciences Campus (UPR-MSC) and the Universidad Central del Caribe (UCC) [PDF]
, 2022 Juan C Soto-Santiago +7 more
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Ethics of translational medical research. [PDF]
Trop Parasitol, 2017 Mandal J, Ponnambath DK, Parija SC.
europepmc +1 more source
Strengthening translational medical research in Ireland: an interdisciplinary framework for clinician–scientist collaboration [PDF]
Colin Joseph McMahon, Walter Kölch
openalex +1 more source
Exploring the translational challenge for medical applications of ionising radiation and corresponding radiation protection research [PDF]
, 2022 Sophie Bockhold +10 more
openalex +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source