Results 131 to 140 of about 54,971,060 (296)

For People with Disabilities Who Need Medical Care “Smart Elephant Whole Body Exercise Machine” Development and Clinical Translational Research [PDF]

, 2023
Seungwan Yang, Jongbae Kim
openalex   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Medical Research Council of Ireland annual report for the year ended 31st December 1983

, 1983
The main remit of the Council is to promote and support medical research and this continues as in previous years, support taking the form of project grants and funding of special research units as well as the Council laboratories in Trinity College ...
Medical Research Council of Ireland
core  

Translational opportunities and barriers for blood-based biomarkers in Alzheimer’s disease: from discovery to implementation

陆军军医大学学报
Alzheimer's disease (AD) is the most common type of dementia in the elderly population, imposed a substantial burden on families and society in China.
WANG Yanjiang, HUANG Shan
doaj   +1 more source

Educational outcomes of a clinical and translational summer research internship program between a private university and a medical school [PDF]

Matthew R. Allen, Melanie E. DeFord
openalex   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Translational Research Part 2

, 2017
Week 2: Translational Research and Big Data 2.2 Translational Research Translational Research Lecture Part 2Demystifying Biomedical Big Data BIOX-201 ...
Haddad, Bassem, Gusev, Yuriy, McGarvey, Peter   +2 more
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Medical Research Council of Ireland annual report for the year ended 31st December 1978

, 1978
The Medical Research Council. is primarily concerned with the excellence and veracity of investigative programmes. The role of medical research is one which is frequently raised by the lay person.
Medical Research Council of Ireland
core  

Dataset for Utilising Large Language Models for the Automated Mapping of Medical Research to Translational Stages

Matthew Clapham, Christopher J. Oldmeadow, Simon Deeming, Carlos Riveros   +3 more
openalex   +2 more sources